Protein Alignment DAT and si:ch211-117c9.5

DIOPT Version :10

• Sequence 1: NP_001261026.1
• Gene: DAT / 36849
• FlyBaseID: FBgn0034136
• Length: 644
• Species: Drosophila melanogaster
• Sequence 2: XP_001922963.4
• Gene: si:ch211-117c9.5 / 100150452
• ZFINID: ZDB-GENE-110408-2
• Length: 652
• Species: Danio rerio
• Alignment Length: 651
• Identity: 279/651 - (42%)
• Similarity: 390/651 - (59%)
• Gaps: 86/651 - (13%)

  Fly     1 MSPTGHISKSKTPTPHDNDNNSISDE--------------------------------------- 26
            |||..|.|         ||..|..||
Zfish     1 MSPEEHFS---------NDGGSCEDESQEDAEVARPLVSETEGSNTDVAEPSVCAGLVDTGDPTA 56

  Fly    27 ------RETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMEL 85
                  |:|||.::||::|.:||||.|.|||||||||||||||.||:||.:|:..||||:|::|:
Zfish    57 ELGHSDRQTWSRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILMVFFGGIPVFFLEI 121

  Fly    86 ALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNN 150
            ||||..::|.:..| .:.|||||:|.|.::|.|:.:.||.:::.|.|.|...|||:||||.:|.:
Zfish   122 ALGQFMKQGGVATW-NIAPLFKGLGLASMVIVFFCNTYYIMVLVWGLYFLAHSFTSSLPWATCGH 185

  Fly   151 IWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVE--GFQSAAS 213
            .|||.||    :.|.|||           ..|||    .::.|.|||:.|| |.:|  |.:|:..
Zfish   186 EWNTINC----TTNFSRV-----------CFNQS----PSHPNNSSLNISA-GCLEPTGLRSSVM 230

  Fly   214 EYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLI 278
            |::.|.:|.|  |.|:.::|.|...|.||||..::|.||.:|||:.::||||:|||:|||.||::
Zfish   231 EFWERKVLRL--SGGLDEVGDISGHMVLCLLATWIIVYFCIWKGVKSAGKVVYFTAVFPYLVLVV 293

  Fly   279 LLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYK 343
            |.:.|::|||:..||.|||.||:|.:.:|:||:|||||:|||...|.|.|.|..|||:::||.|:
Zfish   294 LFVHGVSLPGAINGIIYYLKPNWSKLSEAQVWIDAATQIFFSYAIGLGALTALGSYNRFNNNCYQ 358

  Fly   344 DALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWAL 408
            ||.:.:.|||.|||.||||:|||||:||....|.|.:||..||||.|:.||.|::.||.:..||:
Zfish   359 DAFILALINSGTSFFAGFVVFSVLGFMAAEQDVDISNVAESGPGLAFIAYPKAVSLMPLAPLWAV 423

  Fly   409 IFFMMLLTLGLDSSFGGSEAIITALSDEFPKI----KRNRELFVAGLFSLYFVVGLASCTQGGFY 469
            :||:|||.|||||.|.|.|..||.:.|..|..    ...||:.||......|.:.|:..|:||.|
Zfish   424 LFFLMLLVLGLDSQFVGVEGFITGIMDMLPPKSFIGSLRREVVVAICCFTCFTIDLSMVTEGGMY 488

  Fly   470 FFHLLDRY-AAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLF 533
            .|.|.|.| |:|.::|...|:|.:.|:|:||.:||.:|:..|||:.|..|.:.||.::.|:..:.
Zfish   489 VFQLFDYYSASGITLLWQAFWECVVVAWVYGADRFMDDVACMIGYRPLPYMKWCWSYITPVVCMG 553

  Fly   534 ITVYGLIGYEPLTY-ADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTP- 596
            :.::.::.|:.|.| |.||||.|..||||.:|.||::.||...::|||...|||.:|:..||||
Zfish   554 VFLFHVVNYKRLVYNAVYVYPWWGEALGWFLALSSMLCIPLTVLYKLLHCKGSLMERWQHLTTPI 618

  Fly   597 W 597
            |
Zfish   619 W 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAT	NP_001261026.1	SLC6sbd_SERT-like_u1	27..597	CDD:271405	268/578 (46%)
si:ch211-117c9.5	XP_001922963.4	SLC5-6-like_sbd	63..652	CDD:444915	269/580 (46%)