Protein Alignment Syn2 and Sntg2

DIOPT Version :10

• Sequence 1: NP_788381.1
• Gene: Syn2 / 36848
• FlyBaseID: FBgn0034135
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: XP_006515171.1
• Gene: Sntg2 / 268534
• MGIID: 1919541
• Length: 572
• Species: Mus musculus
• Alignment Length: 484
• Identity: 180/484 - (37%)
• Similarity: 278/484 - (57%)
• Gaps: 36/484 - (7%)

  Fly    25 KVRTGMVHVSD-GKSRPEPLRLNLTMELLSLQKLEVVTPSSCHPNGPPMESKERMVQITRQKQGG 88
            :.:|.:..:.| |......:||.||.|:|::||.:||    |....|| .:..|.|.:.||..||
Mouse    24 RTKTALALLYDEGLENAYDVRLKLTKEVLTIQKQDVV----CIGGAPP-GANHRTVTLRRQPVGG 83

  Fly    89 LGLSIKGGAEHKLPILISRIYKDQAADITGQLFVGDAIIKVNGEYITACPHDDAVNILRNAGDIV 153
            |||||||||||.:|::||:|:||||||.|..||:|||:::|||..:....|::.|::||||||.|
Mouse    84 LGLSIKGGAEHGVPVVISKIFKDQAADQTEMLFIGDAVLQVNGINVENATHEEVVHLLRNAGDDV 148

  Fly   154 VLTVKHYRAATPFLQKQLTKDTPDSDNDVTCAELKADEG-YKSSVNSGTISRSCSRPMSICSEP- 216
            .:||::.|.|..||:..|....|.||:....:....|.| :.:...|.|...|.|.|  |.:||
Mouse   149 TITVEYLREAPSFLKLPLGSPGPSSDHSSRASSPLFDSGLHLNGHCSHTAPSSPSSP--IANEPK 211

  Fly   217 -EKRWTDVVAVPLMMAYVTRYIYGTDKLRQNAFEVRGLNGISTGVIHCDELAILSQWLKLITDNV 280
             ||||.|.::|||.||.::||..||:|||.:|.||..|:|.||||:........:.||:.|:.|:
Mouse   212 YEKRWLDTLSVPLSMARISRYKAGTEKLRSSALEVLALDGASTGVLQFSTAQDCADWLRSISTNI 276

  Fly   281 VGLTHLQMKLYNRNFAVGERIEYMGWVNE---GVINNNISWQSYKPRFLLLKGTEVMLFETPPLN 342
            ..||...||:.|:..:..:::.:||||||   |..|:    |:::|:||.|:|:...:|..||::
Mouse   277 SDLTLQHMKMANKCCSPCDQVVHMGWVNERLQGADNS----QNFRPKFLALRGSSFYIFGAPPVS 337

  Fly   343 VAGISKALVVYKVYQTMFRI------------------VKESETVDSRQHCFLLQSSGHEPRYLS 389
            .....:|...|.:.:.:|::                  :::.:..|.|.:||.:.::..:....|
Mouse   338 TLDWGRAERAYNLCEVLFKVHKFWLSDNYWLQANLYLGLQDFDCEDPRSYCFSVLANHGKSHIFS 402

  Fly   390 VETRQELLRIENSWNAAIVTSVIKLGRKTFAVSHHGKSGGLTLDWQAGFSLTEGAESATVWQYKF 454
            ||...||...|.::..|....|.:.|.||:..|..|::...|:|:..||:..:|.....:|::||
Mouse   403 VELGSELAVWEKAFQRATFMEVQRTGSKTYLCSWQGETLCFTVDFALGFTCFDGKTKNVLWRFKF 467

  Fly   455 SQLRGSSDDGKSKLKLHFQDHDSRAIETK 483
            |||:|||||||:::||.||:.|::.||||
Mouse   468 SQLKGSSDDGKTRVKLLFQNLDTKQIETK 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn2	NP_788381.1	PDZ_syntrophin-like	77..159	CDD:467262	47/81 (58%)
		PH	301..407	CDD:214574	30/126 (24%)
Sntg2	XP_006515171.1	PDZ_syntrophin-like	72..154	CDD:467262	47/81 (58%)