DRSC/TRiP Functional Genomics Resources

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Protein Alignment loopin-1 and Npepl1

DIOPT Version :10

Sequence 1:NP_611134.1 Gene:loopin-1 / 36847 FlyBaseID:FBgn0259795 Length:526 Species:Drosophila melanogaster
Sequence 2:NP_001365722.1 Gene:Npepl1 / 228961 MGIID:2448523 Length:529 Species:Mus musculus


Alignment Length:378 Identity:99/378 - (26%)
Similarity:150/378 - (39%) Gaps:60/378 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   155 EQAAEGAALA------VWRYNANKRKKNRIQTPKLDMYGKGDRDAWVRGL----FKAESQNLARR 209
            |..|...|||      ..|..|::|.:.|....:..:.|:.:....|..|    ...|...||.|
Mouse   124 EVFASACALARAFPLFTHRSGASRRAEKRTVMVEFFLVGQDNGPVEVSTLQCLTNATEGVRLAAR 188

  Fly   210 LSDTPANMMTPSIFAQAAVDALCPCGVSVEVRSMDWIEDMNLNSFLMIAKGSCEPPLLLECSYCG 274
            :.|||.|.|...||.:..:......|::..:...:.::.........:.|.:..||.|...|:  
Mouse   189 IVDTPCNEMNTDIFLEEIIQVGKELGITPTIIRDEQLKTKGFGGIYGVGKAALHPPALAILSH-- 251

  Fly   275 TTPE--DRPVLLLGQGLTFHSGGLCLKPKTGMDQYRGAMAGAAVCVGVLRAAAALSLPLNITAVM 337
             ||:  .:.:..:|:|:.:.:|||.:|.||.|...:....|||..:|..|||.......|:.||.
Mouse   252 -TPDGATQTIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGAAAVLGAFRAAIKQGFKDNLHAVF 315

  Fly   338 PLCEHMPSGMAVKCGDVVTLLNGTTMGIKNVDKAPVVQLADPLLYAQATYKPKLVIDIGTVAMGV 402
            .|.|:.....|.:..|:..|.:|.|:.|.|.|....:.|||.:.||.......:::|:.|:.   
Mouse   316 CLAENAVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADGVSYACKDLGADIIVDMATLT--- 377

  Fly   403 NYAVGGGASGLWT--------TSKSVWQ-NFRKSGGLTGDRVWRFPL-------FKYYKQIV--N 449
                  ||.|:.|        |:.:.|: ...|:|...||.|  .||       |..:...|  .
Mouse   378 ------GAQGIATGKYHAAVLTNSAEWEAACVKAGRKCGDLV--HPLVYCPELHFSEFTSAVADM 434

  Fly   450 KNITYDLCNTGRGPASSCLAAAILHTL---VPCAEWAHLDI--------RGTG 491
            ||...|..|:    .|||....|...:   .| ..|.||||        |.||
Mouse   435 KNSVADRDNS----PSSCAGLFIASHIGFDWP-GVWVHLDIAAPVHAGERATG 482

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
loopin-1NP_611134.1 Peptidase_M17_N 44..173 CDD:426984 7/23 (30%)
Peptidase_M17 206..514 CDD:459978 86/317 (27%)
Npepl1NP_001365722.1 Peptidase_M17 35..492 CDD:238247 99/378 (26%)

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