Protein Alignment Sema2a and sema3fb

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_009304469.2
• Gene: sema3fb / 799945
• ZFINID: ZDB-GENE-050513-2
• Length: 791
• Species: Danio rerio
• Alignment Length: 677
• Identity: 201/677 - (29%)
• Similarity: 312/677 - (46%)
• Gaps: 121/677 - (17%)

  Fly    54 GADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRD--VINLEPTRDDVV 116
            |..|...|......||...|:||.|.:|||:.|.:..::|.:|     ||:  :|:...:.....
Zfish    43 GTAHYFSFLLNTSDYRILRMDEDHDRMYVGSKDYILSLDLHDI-----NREPLIIHWPVSPQRKT 102

  Fly   117 SCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRS----------- 170
            .||..||....:|.|.:|:|:..:: ..||:|||.|:||  ...|.|....|.:
Zfish   103 ECVLSGKDTNGECGNFIRLIEPWNR-THLYICGTGAYNP--VCTYVNRGRKPMTAMHLQMPQTRG 164

  Fly   171 ------------------EYVIGV-----GLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTN 212
                              |||..:     ..|..||||||..||.:..: ||.      ||:|..
Zfish   165 RASRAAEPETVFDETGLQEYVFHLEPGKEDSGKGKCPYDPKLNSVSALI-NGE------LYAGVY 222

  Fly   213 AEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSF---DIGE----YVYFFFR 270
            .:|...|:.||||...|.        ..||.:|:|:||:.|:||...   |.||    .:|||||
Zfish   223 IDFMGTDSAIFRTLGKNA--------VMRTDQYNSRWLNDPSFVHVHLIPDSGEKNDDKLYFFFR 279

  Fly   271 ETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISGE--FPFYFNEIQSVYQ 333
            |.:.|.....|: .|||.|:|..|.||...|.:.|:|:|||||.||:.|.  ...:|:|::.||.
Zfish   280 EKSSEMGQSPKS-QSRIGRICLNDDGGHCCLVNKWSTFLKARLICSVPGADGIETHFDELRDVYI 343

  Fly   334 LPSDKSR---FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPR 395
            .|:..::   .:..|:.|.:...|||||.:.:.:|:..|||.|..:...|..|: ....::|.||
Zfish   344 QPTQDTKNPVIYGVFSVSGSVFKGSAVCVYSMADIRMVFNGPFAHKEGPNYQWV-AYTGKIPYPR 407

  Fly   396 PGTC--------VNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKR--DLVFTKLVVDKIRI 450
            ||||        :..|.:.||.|:||:|:||.|..:|...|..|:..:.  |..||.:.||  ::
Zfish   408 PGTCPGGTFTPNMKSTKDYPDEVINFMRNHPTMYNSVYPVHKRPLVVRTNVDYEFTTITVD--QV 470

  Fly   451 DILNQEYIVYYVGTNLGRIYKIV----QYYRNGESLSKLLDIFEVAPNEAIQVMEISQTRKSLYI 511
            ...:..|.|.::||:.|.:.|::    ...:..|.:.:.:::|:|.  .:|..|:||..|:.||:
Zfish   471 TAADGNYEVLFLGTDKGTVQKVIVLPSDDLQTEELVLEEVEVFKVP--TSITTMKISSKRQQLYV 533

  Fly   512 GTDHRIKQIDLAMCNRRYDNCFRC--VRDPYCGWDKEANTCR---------PYELDLLQDV--AN 563
            .:...:..:.|..|:...:.|..|  .|||||.||  ..:|.         |:.....|||  .|
Zfish   534 ASAVGVTHMALHRCDVYGEACADCCLARDPYCAWD--GKSCSRYSASQKRLPFRRSRRQDVKYGN 596

  Fly   564 ETSDIC---DSSVLKKKI-VVTY---GQSVHLGCFVKIPEVLKNEQVTWY-HHSKDKGRYEIRYS 620
            .... |   :|::.|..: .|.|   |.|..|.|..:.|    :..:.|: |......|.|:| |
Zfish   597 PIRQ-CRGYNSNINKNTLETVQYGVEGSSTFLECQARSP----HAAIKWHLHRDNSDRRREVR-S 655

  Fly   621 PTKYIETTERGLVVVSVNEADGGRYDC 647
            ..:.:: |::||::.|:..:|.|.|.|
Zfish   656 DGRVLK-TDQGLLLRSLQSSDSGIYIC 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	157/518 (30%)
		Ig_Semaphorin_C	573..664	CDD:143180	22/80 (28%)
sema3fb	XP_009304469.2	Sema_3F	48..547	CDD:200515	159/527 (30%)
		PSI	546..>582	CDD:214655	11/37 (30%)
		Ig_Semaphorin_classIII	612..700	CDD:143279	21/76 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X596
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910