Protein Alignment Sema2a and si:ch211-129c21.1

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_005170527.1
• Gene: si:ch211-129c21.1 / 563087
• ZFINID: ZDB-GENE-030131-5796
• Length: 791
• Species: Danio rerio
• Alignment Length: 735
• Identity: 219/735 - (29%)
• Similarity: 336/735 - (45%)
• Gaps: 152/735 - (20%)

  Fly    34 YYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISS 98
            |.:....|..:||..||.                  |..:.||...|.:||.:.||.:::.:||.
Zfish    34 YEDNHAITFKEQGIWNYS------------------TMLIREDLGLLVLGAREAVFALDINDISV 80

  Fly    99 SNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPK-DYVIYA 162
            |   |..:..:.|.:....|.||||....||.|::|::..|:. ..:|:|||||.:|. ||:.|.
Zfish    81 S---RSKVLWKVTEEKQKECTSKGKHPDIDCHNYIRMLHQMND-SVMYICGTNAFSPTCDYITYD 141

  Fly   163 NLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDL 227
            |.......:...|.|    |||:||...|:::.|:.       .|||.|:..|..::.||.||..
Zfish   142 NGQLQLEGKQEDGRG----KCPFDPFQRSSSVMVDQ-------DLYSATSLNFLGSEPVILRTSP 195

  Fly   228 YNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDIGE----------YVYFFFRETAVEYINCGKA 282
            ...          ||| ..|.||::|||:....:.|          .:|.||.|.|:||....|.
Zfish   196 ITL----------RTL-LKSSWLNEPNFIYMDAVPESEDSPEGDDDKIYMFFSENAIEYDFYNKL 249

  Fly   283 VYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSI-SGEFPFYFNEIQSVYQLPSDKSRFFATFT 346
            |.||:|||||.|:||...|...|.::|||||:||: ....|:...::..|......||.|:|.||
Zfish   250 VVSRVARVCKGDMGGLRTLQRKWTSFLKARLDCSVPEPSLPYVIQDVFHVRHQKWRKSVFYAIFT 314

  Fly   347 TSTNGL-IGSAVCSFHINEIQAAFN-GKFKEQ---SSSNSAWLPVLNSRVPEPRPGTCVNDTS-- 404
            :.::.. ..||||::::.:|...|: ||||.:   ..|:..|: ..:..:|.||||.|:|:.:
Zfish   315 SQSSSTDQSSAVCAYNVTDISNVFSRGKFKTEVAVEMSDVKWV-TYSGDLPVPRPGDCINNAART 378

  Fly   405 -------NLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKI-RIDILNQEYIVYY 461
                   |:||..|.|||..||||.||:.....|:..||..:.|:||||.: ..|  .|.|.:.:
Zfish   379 SGIKSSMNIPDKTLQFIRDRPLMDDAVHPITGKPLLLKRGPLLTRLVVDMVTAAD--GQSYPMMF 441

  Fly   462 VGTNLGRIYKIVQYYRNGE-SLSKLLDIFEVAPNEAIQVMEISQTRKSLYIGTDHRIKQIDLAMC 525
            |||..|.:.|.|.|  :|| .:.:.:.:||  ..|||.|:.:.|.:  ||.|:...:.|:.::.|
Zfish   442 VGTANGYVQKAVNY--DGEMHIIEEVKLFE--SEEAIDVLRLHQNQ--LYAGSASGVVQMPVSNC 500

  Fly   526 NRRYDNCFRCV--RDPYCGWDKEANTCRPY-------ELDLLQDVANETSDICD-SSVLKKKI-V 579
            : ||.:|..||  |||||.||..|..|..:       :.:|:|.:.:..:..|. ::.::.|: .
Zfish   501 S-RYSSCLDCVLARDPYCAWDVPAQRCSRFPASTEHAKSNLIQSLKDGDATQCPITAPIEPKVRT 564

  Fly   580 VTYGQSVHLGCFVKIPEVLKN-EQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGG 643
            :..|.::.|.|   .|:  .| .||.|....|     .:.:|..||....: .:::.:.:.||.|
Zfish   565 LVLGNNIRLLC---RPD--SNLAQVNWNLAGK-----PLPFSNRKYTIYND-AILISNASSADAG 618

  Fly   644 RYDCHLGGSLLCSYNITVDAHRCTPPNKSNDYQK---IYSDWCHE------FEKYKTAMKSWEKK 699
            ||.|           ::|:      ..|...|.|   ||.  .||      .:|.||.:..
Zfish   619 RYTC-----------VSVE------QAKGKHYTKTLAIYD--LHEEVAVVVTDKIKTTLGI---- 660

  Fly   700 QAQCSTRQNFSSNQHPNEIF 719
                           ||||:
Zfish   661 ---------------PNEIY 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	161/484 (33%)
		Ig_Semaphorin_C	573..664	CDD:143180	20/92 (22%)
si:ch211-129c21.1	XP_005170527.1	Sema_4E	42..498	CDD:200521	165/508 (32%)
		PSI	499..553	CDD:214655	17/54 (31%)
		Ig_Sema4D_like	558..644	CDD:143281	25/115 (22%)
		IG_like	560..623	CDD:214653	19/84 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010