Protein Alignment Sema2a and Sema6a

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_003751830.1
• Gene: Sema6a / 361324
• RGDID: 1305493
• Length: 1048
• Species: Rattus norvegicus
• Alignment Length: 682
• Identity: 215/682 - (31%)
• Similarity: 329/682 - (48%)
• Gaps: 110/682 - (16%)

  Fly     9 LLALLLLLCSSVSETAADYE----NTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYYR 69
            ||.|.||.|:... ...|.|    :..|:..:.|...|:..|.|...:|..|          ...
  Rat     7 LLCLTLLRCAGAG-FPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHRLD----------IQM 60

  Fly    70 TFHMNEDRDTLYVGAMDRVFRVNLQNISSSN--CNRDVINLEPTRDDVVSCVSKGKSQIFDCKNH 132
            ...||.   |||:.|.|.::.|::....:..  |::. :..:..:.||.:|..|||.: .:|.|.
  Rat    61 IMIMNR---TLYIAARDHIYTVDIDTSHTEEIYCSKK-LTWKSRQADVDTCRMKGKHK-DECHNF 120

  Fly   133 VRVIQSMDQGDRLYVCGTNAHNP--KDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIY 195
            ::|:...:. |.|:||||||.||  ::|.:....|.  ..|:     .|:|:||||....:.|::
  Rat   121 IKVLLKKND-DTLFVCGTNAFNPSCRNYRVDTLETF--GDEF-----SGMARCPYDAKHANIALF 177

  Fly   196 VENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFD 260
            .:.       .|||.|..:|...|.||:|: |.::..       .||:|:|||||.:|.||.:.|
  Rat   178 ADG-------KLYSATVTDFLAIDAVIYRS-LGDSPT-------LRTVKHDSKWLKEPYFVQAVD 227

  Fly   261 IGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGG-KNLLAHNWATYLKARLNCSISGEFPFY 324
            .|:|:||||||.||||...||.|:.|:|:|||.|:|| :.:|...|.::||||||||:.|:..||
  Rat   228 YGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFY 292

  Fly   325 FNEIQSVYQLPSDKSR--FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVL 387
            ||.:|:|..:.....|  ..|||:|..|.:.|||||::.:.:|...|.|:||||.|.:|.|.||.
  Rat   293 FNILQAVTDVIRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIANVFTGRFKEQKSPDSTWTPVP 357

  Fly   388 NSRVPEPRPGTCVND-------TSN-LPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLV---FT 441
            :.|||:||||.|...       ||| .||..||||::|||||:||....|.| ::.|.:|   .|
  Rat   358 DERVPKPRPGCCAGSSSLEKYATSNEFPDDTLNFIKTHPLMDEAVPSIINRP-WFLRTMVRYRLT 421

  Fly   442 KLVVDKIRIDILNQEYIVYYVGTNLGRIYKIV-----QYYRNGESLSKLLDI-------FEVAPN 494
            |:.||.......|  :.|.::|:..|.|.|.:     ..:.||....:.:::       ::...:
  Rat   422 KIAVDNTAGPYEN--HTVVFLGSEKGIILKFLARIGSSGFLNGSLFLEEMNVYNPEKCSYDGVED 484

  Fly   495 EAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFR-CV--RDPYCGWDKEANTCRPY--- 553
            :.|..|::.:...|||:.....:.::.|..| .|:..|.: |:  |||||||.||..:|...
  Rat   485 KRIMGMQLDKASGSLYVAFSTCVIKVPLGRC-ERHGKCKKTCIASRDPYCGWVKETGSCAHLSPL 548

  Fly   554 -ELDLLQDVANETSD---ICDSSVLKKKIVVTYGQSVHLGCFVKIPEVLKNEQVTWYHHSKDKGR 614
             .|...||:....:|   .|.:|.:....:.|           .:|:...:....:       ||
  Rat   549 SRLAFEQDIERGNTDGLGDCHNSFVALNDIST-----------PLPDYEMSFNTVY-------GR 595

  Fly   615 YEIRYSPTKYIETTERGLVVVSVNEADGGRYD 646
            ....|..|...::..|     ..:|:.||..|
  Rat   596 ASSLYPSTTTSDSASR-----DGHESQGGMLD 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	168/486 (35%)
		Ig_Semaphorin_C	573..664	CDD:143180	11/74 (15%)
Sema6a	XP_003751830.1	Sema_6A	48..513	CDD:200527	171/505 (34%)
		PSI	514..>544	CDD:396154	14/30 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010