Protein Alignment Sema2a and sema6a

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_956286.1
• Gene: sema6a / 336060
• ZFINID: ZDB-GENE-030131-8004
• Length: 968
• Species: Danio rerio
• Alignment Length: 644
• Identity: 210/644 - (32%)
• Similarity: 320/644 - (49%)
• Gaps: 99/644 - (15%)

  Fly    11 ALLLLLCSSVSETAADYENT-------WNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLYY 68
            ||||.|....:..||..|:|       .|:..:.|...|:..|.||..:|..|          ..
Zfish     5 ALLLYLTLLQTAGAAFPEDTEPISIAHGNYTKQYPVFVGHKPGRNNTQRHKLD----------IQ 59

  Fly    69 RTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNC-NRDVINLEPTRDDVVSCVSKGKSQIFDCKNH 132
            ....||.   ||||.|.|.::.::::..|:... ....:..:..:.||.:|..|||.: .:|.|.
Zfish    60 LIVIMNR---TLYVAARDHIYTLDMETSSTEEIFFSKKLTWKSRQADVDTCRMKGKHK-DECHNF 120

  Fly   133 VRVIQSMDQGDRLYVCGTNAHNP--KDYVIYANLTHLPRSEYVIGVG---LGIAKCPYDPLDNST 192
            ::|:....: |.|:||||||.||  :.|          |.:.:..:|   .|:|:||||....:.
Zfish   121 IKVLLQQSE-DSLFVCGTNAFNPSCRTY----------RMDSLDALGEEISGMARCPYDAKHANV 174

  Fly   193 AIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVG 257
            |::.:.       .|||.|..:|...|.||:|: |.::..       .||:|:|||||.:|.||.
Zfish   175 ALFADG-------KLYSATVTDFLAIDAVIYRS-LGDSPT-------LRTVKHDSKWLKEPYFVQ 224

  Fly   258 SFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGG-KNLLAHNWATYLKARLNCSISGEF 321
            :.|..:::||||||.|:||.:.||.|:.|:|||||.|.|| :.:|...|.::||.||||||.|:.
Zfish   225 AVDYEDFIYFFFREIAMEYNSMGKVVFPRVARVCKSDSGGSQRVLEKQWTSFLKTRLNCSIPGDS 289

  Fly   322 PFYFNEIQSVYQL--PSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWL 384
            .||||.:|:|..:  .|.:....|||:|..|.:.|||||::.::||..||.|:||||.|.:|.|.
Zfish   290 HFYFNILQAVTDVIHISGRDVVMATFSTPYNSIPGSAVCAYDMSEIALAFTGRFKEQKSPDSTWT 354

  Fly   385 PVLNSRVPEPRPGTCVND--------TSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVF- 440
            ||...|||:||||.|...        :|..||..|:||::||||::||....|.|.:.|..:.:
Zfish   355 PVPEERVPKPRPGVCAGSSSVEKFKVSSEFPDDSLSFIKAHPLMEEAVPAIANRPWFLKTMVRYR 419

  Fly   441 -TKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNGESLSKL----LDIFEV-------AP 493
             |::.||.....  :..:.|.::|:..|.:.|.:...|:|.....|    |:::..       ..
Zfish   420 LTRIAVDNAAGP--HSNHTVVFLGSERGIVLKFLAKIRSGALNDSLFLEELNVYNAEKCSIDGVE 482

  Fly   494 NEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFR-CV--RDPYCGWDKEANTCR---- 551
            ::.|..|:|....:||::.....:.::.||.| :|:..|.: |:  |||||||..| ..||
Zfish   483 DKRIISMQIDSRSRSLFVAFSSCVVRVPLARC-QRHGKCKKSCIASRDPYCGWVSE-GACREITS 545

  Fly   552 ----PYELDLLQDVANETSDICDSSVLKKKIVVTYGQSVHLGCFVKIP----EVLKNEQ 602
                |:|.|:.|...:...|..:|.|.....|.:...|   ...|.:|    .|||:.|
Zfish   546 DAKWPFEQDVEQGNTDGLGDCQNSFVALNGRVSSPSVS---PAVVSVPLGRGRVLKDHQ 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	162/486 (33%)
		Ig_Semaphorin_C	573..664	CDD:143180	9/34 (26%)
sema6a	NP_956286.1	Sema	48..512	CDD:301699	166/505 (33%)
		PSI	513..>545	CDD:279745	14/33 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910