Protein Alignment Sema2a and Sema7a

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001101623.1
• Gene: Sema7a / 315711
• RGDID: 1305192
• Length: 666
• Species: Rattus norvegicus
• Alignment Length: 686
• Identity: 166/686 - (24%)
• Similarity: 277/686 - (40%)
• Gaps: 149/686 - (21%)

  Fly    10 LALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKH------GADHVREFNCGKLYY 68
            |.|.|||...|:..:|                   ||::..|..      |.||| :|...:.:.
  Rat    29 LRLRLLLVFWVTAASA-------------------QGHSRSGPRISAVWKGQDHV-DFGQPEPHN 73

  Fly    69 RTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHV 133
            ..|| .....:::||...:|:..|..  ...|.:...:|:..|:.   ||..|.     ||:|::
  Rat    74 VLFH-EPGSFSVWVGGRGKVYLFNFP--EGKNASVRTVNIGSTKG---SCQDKQ-----DCENYI 127

  Fly   134 RVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYVEN 198
            .:::.  :|:.|.||||||..|..:       :|.....|:.:|......|:.|.:||
  Rat   128 TLLER--RGNGLLVCGTNARKPSCW-------NLVNDSVVMSLGEMKGYAPFSPDENS------- 176

  Fly   199 GNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFK----RTLKYDSKW------LDKP 253
                                 .|:|..|...::.::.||..|    |.::.:|:.      :..|
  Rat   177 ---------------------LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNP 220

  Fly   254 NFV--------GSFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLA-HNWATYL 309
            .|:        .::|  :.:|:||||...:.........||:|::|:.|.||::.|: ..|.|:|
  Rat   221 QFIKATIVHQDQAYD--DKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 283

  Fly   310 KARLNCSISGEFPFYFNEIQSVYQLPSDK-----SRFFATFTTSTNGLIGSAVCSFHINEIQAAF 369
            ||.|.|| .......||.:|.|:.||...     :|.:..|:...|   .||||.:.:.:|...|
  Rat   284 KAMLVCS-DAATNRNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWN---YSAVCVYSLGDIDRVF 344

  Fly   370 NGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYY 434
                  ::||    |...:..:|.||||.|:.....:|........|||.:.:.|  |...|:
  Rat   345 ------RTSS----LKGYHMGLPNPRPGMCLPKKQPIPTETFQVADSHPEVAQRV--EPMGPL-- 395

  Fly   435 KRDLVFTKLVVDKI---RIDILNQE-YIVYYVGTNLGRIYKIVQYYRNGESLSKLLDIFEVAP-- 493
            |..|..:|....|:   |:...|.| :.|.|:.|:.|.|:|:|:  ...:..|.:.:|.|:.|
  Rat   396 KTPLFHSKYHYQKVVVHRMQASNGETFHVLYLTTDRGTIHKVVE--SGDQEHSFVFNIMEIQPFH 458

  Fly   494 -NEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRCV--RDPYCGWDKEANTC---RP 552
             ..|||.:.:...|:.||:.:...:.|:.|.||......|..|:  ||||||||::.:.|   ..
  Rat   459 RAAAIQAISLDADRRKLYVTSPWEVSQVPLDMCGVYSGGCHGCLMSRDPYCGWDQDQDRCVSIYS 523

  Fly   553 YELDLLQDV-ANETSDIC-----DSSVLKKKIVVTYGQSVHLGCFVKIPEVLKNEQVTWYHHSKD 611
            .:..:||.: ..|....|     |.:.| :|:.:......:|.|    |...::....|.|....
  Rat   524 SQRSVLQSINPAEPHRECPNPNPDEAPL-QKVSLARNSRYYLTC----PMESRHATYLWRHEENV 583

  Fly   612 KGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDC 647
            :...|..:.....|      |.:.::.....|.|.|
  Rat   584 EQSCEPGHQSPSCI------LFIENLTARQYGHYRC 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	119/487 (24%)
		Ig_Semaphorin_C	573..664	CDD:143180	13/75 (17%)
Sema7a	NP_001101623.1	PSI	491..>520	CDD:279745	12/28 (43%)
		Ig	549..622	CDD:299845	13/76 (17%)
		Sema_7A	70..489	CDD:200504	119/488 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000