Protein Alignment Sema2a and Sema3g

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001094352.1
• Gene: Sema3g / 290562
• RGDID: 1306079
• Length: 780
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 187/643 - (29%)
• Similarity: 285/643 - (44%)
• Gaps: 101/643 - (15%)

  Fly    64 GKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFD 128
            |.|..:..:::|.||.|::|..|.::.:.|......  .|:|: ..|.....|.||.|||..:.:
  Rat    55 GSLDLQVMYLDEYRDRLFLGGRDALYSLRLDQAWPD--PREVL-WPPQPGQKVECVRKGKDPLTE 116

  Fly   129 CKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVI-----GVGLGIAKCPYDPL 188
            |.|.|||:|..:: ..|..|||.|..|    |...:|...|.|:|:     .:..|..:||::|.
  Rat   117 CANFVRVLQPHNR-THLLACGTGAFQP----ICTFITVGHRGEHVLHLDPSSIENGRGRCPHEPS 176

  Fly   189 DNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTD-----LYNTSAKRLEYKFKRTLKYDSK 248
            ....:.:|     ||  .||:|..|:|...:.:|||:.     |.:.|              |..
  Rat   177 RPFASTFV-----GG--ELYTGLTADFLGREAMIFRSGGPRPALRSDS--------------DQS 220

  Fly   249 WLDKPNFVGSFDI-------GEYVYFFFRETAVEYI-NCGKAVYSRIARVCKKDVGGKNLLAHNW 305
            .|..|.||.:..|       .:.|||||.||..... ..|....||:.|||..|.||:.:|.:.|
  Rat   221 LLHDPRFVMAARIPDNSDRDDDKVYFFFSETVPSPDGGPGHVTVSRVGRVCVNDAGGQRVLVNKW 285

  Fly   306 ATYLKARLNCSISGE--FPFYFNEIQSVYQL---PSDKSRFFATFTTSTNGLIGSAVCSFHINEI 365
            :|:|||||.||:.|.  ...:|::::.|:.|   .......:|.|:|.:....|.|||.:|:.:|
  Rat   286 STFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKNLEVYALFSTVSAVFRGFAVCVYHMVDI 350

  Fly   366 QAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTC-----------VNDTSNLPDTVLNFIRSHPL 419
            ...|||.|..:......|.| ...:||.||||.|           ...|.:.||.||.|:|.|||
  Rat   351 WEVFNGPFAHRDGPQHQWGP-YGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRGHPL 414

  Fly   420 MDKAVNHEHNNPVYYKRDLV--FTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNG--- 479
            |.:.|......||..|..|.  ..::|||  |::..:..|.|.::||:.|.:.||:....:|
  Rat   415 MFQPVRPRRGRPVLVKTHLAQQLCQIVVD--RVEAEDGTYDVIFLGTDSGSVLKIIALQGSGLPE 477

  Fly   480 --ESLSKLLDIFEVAPNEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRC--VRDPY 540
              |.:.:.|.:|:|.  ..|..||||..|::||:|:...:.::.|..|......|..|  .||||
  Rat   478 PEEVVLEELQVFKVP--TPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPY 540

  Fly   541 CGWDKEANTCRPYELD------LLQDVANETSDI-C--------DSSVLKKKIVVTYGQSVHLGC 590
            |.||  ..:|..|...      ..||:.:....: |        .:|.|..::..|...|..|.|
  Rat   541 CAWD--GTSCARYRPSSGKRRFRRQDIRHGNPAVQCLGQGQSQDKASGLVTRVFGTEHNSTFLEC 603

  Fly   591 FVKIPEVLKNEQVTWY-HHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDC 647
            ..|.|:.    .|.|: ....|||..:::  ..:.:..|::||:...::..|.|.|.|
  Rat   604 RPKSPQA----AVRWFLQRPGDKGADQVK--TDERVVQTDQGLLFRRLSRLDAGNYTC 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	150/497 (30%)
		Ig_Semaphorin_C	573..664	CDD:143180	19/76 (25%)
Sema3g	NP_001094352.1	Sema	50..523	CDD:301699	152/501 (30%)
		PSI	522..568	CDD:214655	14/47 (30%)
		Ig_Semaphorin_classIII	591..676	CDD:143279	18/71 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45857
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910