Protein Alignment Sema2a and Sema2b

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 489/723 - (67%)
• Similarity: 598/723 - (82%)
• Gaps: 8/723 - (1%)

  Fly     3 LLQLSPLLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKLY 67
            |..||.||.:|:.....|....||||||||.|||.|||||:...  ::.:|..:||::|:||.|:
  Fly    59 LCSLSALLLVLVAQTVHVEYARADYENTWNLYYEPPCCTGSSAA--HHLRHHKEHVQDFSCGPLH 121

  Fly    68 YRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNH 132
            |:||:|:|..:.||||||||:||:||:|||.|.|.|||:.||||..|:::||||||.:..:|:||
  Fly   122 YKTFYMDERNNALYVGAMDRIFRLNLRNISQSICERDVLILEPTGSDILNCVSKGKREKVECRNH 186

  Fly   133 VRVIQSMD-QGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIYV 196
            :||||.|: .|.:||||||||||||||||.|||||||||:||.|:||||.||||||.|||||:||
  Fly   187 IRVIQPMNFNGQKLYVCGTNAHNPKDYVINANLTHLPRSQYVPGIGLGIGKCPYDPADNSTAVYV 251

  Fly   197 ENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFDI 261
            |||||.|||.||:||||||||||:||||:||||.:..|.|..||||:|||||.||||||||||:|
  Fly   252 ENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSKLLDKPNFVGSFEI 316

  Fly   262 GEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISGEFPFYFN 326
            ||:|||||||.||||||||||||||:|||||.|.|||.:::.|||||||||:|||||.|||||||
  Fly   317 GEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARMNCSISSEFPFYFN 381

  Fly   327 EIQSVYQLPSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRV 391
            ||||||::|:|.::|:|||||:|||||||||||:.|.:|.|||:||||||::|||||||||||:|
  Fly   382 EIQSVYKMPTDDTKFYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQATSNSAWLPVLNSKV 446

  Fly   392 PEPRPGTCVNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQE 456
            ||||||||.|||:.|||:||||||.||||||||:||..|||::|||::.|||||||||||.||||
  Fly   447 PEPRPGTCHNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDVILTKLVVDKIRIDKLNQE 511

  Fly   457 YIVYYVGTNLGRIYKIVQYYRNGESLSKLLDIFEVAP-NEAIQVMEISQTRKSLYIGTDHRIKQI 520
            ::||:|.|..|.||||||:...|:..|.|:||||.:| :|.|:.|.:|....|||:.|||::|||
  Fly   512 FLVYFVATTSGHIYKIVQFMHYGQRHSNLVDIFEASPHSEPIREMTLSHKTGSLYVATDHQVKQI 576

  Fly   521 DLAMCNRRYDNCFRCVRDPYCGWDKEANTCRPYELDLLQDVANETSDICDSSVLKKKIVVTYGQS 585
            |:|||.||||:|||||.||||||||:.|.||||:|.||||||||||.|||:|||:||:..:|||:
  Fly   577 DIAMCARRYDSCFRCVSDPYCGWDKDVNACRPYQLGLLQDVANETSGICDTSVLRKKVTSSYGQT 641

  Fly   586 VHLGCFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLG 650
            :||.||||:||||:.:|..|||||.:|||||:||:|||||:|.|.|||:::|||.||||||.:|.
  Fly   642 LHLSCFVKMPEVLRKKQTRWYHHSTEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGDGGRYDSYLD 706

  Fly   651 GSLLCSYNITVDAHRCTPPNKSNDYQKIYSDWCHEFEKYKTAMKSWEKKQAQCSTRQN---FSSN 712
            |:|||||.:|||||||:||::..|||||||.||:||||||:|||.|:.||.||..:..   .|||
  Fly   707 GTLLCSYGVTVDAHRCSPPSQKQDYQKIYSHWCNEFEKYKSAMKQWQAKQEQCGLKDKTGPISSN 771

  Fly   713 -QHPNEIF 719
             :|.|::|
  Fly   772 GKHVNDVF 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	326/458 (71%)
		Ig_Semaphorin_C	573..664	CDD:143180	59/90 (66%)
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	326/458 (71%)
		Ig	632..720	CDD:299845	57/87 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456992
Domainoid	1	1.000	68	1.000	Domainoid score	I9670
eggNOG	1	0.900	-	-		E1_KOG3611
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	264	1.000	Inparanoid score	I1881
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D13916at7147
OrthoFinder	1	1.000	-	-		FOG0007625
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_113396
Panther	1	1.100	-	-	P	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X596
	10	9.800