Protein Alignment Sema2a and Sema3g

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001020550.1
• Gene: Sema3g / 218877
• MGIID: 3041242
• Length: 780
• Species: Mus musculus
• Alignment Length: 650
• Identity: 194/650 - (29%)
• Similarity: 288/650 - (44%)
• Gaps: 114/650 - (17%)

  Fly    64 GKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFD 128
            |.|..:..:::|.||.|::|:.|.::.:.|......  .|:|:.| |.....|.||.|||..:.:
Mouse    54 GSLDLQVMYLDEYRDRLFLGSRDALYSLRLDQAWPD--PREVLWL-PQPGQKVECVRKGKDPLTE 115

  Fly   129 CKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVI-----GVGLGIAKCPYDPL 188
            |.|.|||:|..:: ..|..|||.|..|    |...:|...|.|:|:     .|..|..:||::|.
Mouse   116 CANFVRVLQPHNR-THLLACGTGAFQP----ICTFITVGHRGEHVLRLDASSVENGRGRCPHEPS 175

  Fly   189 DNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTD-----LYNTSAKRLEYKFKRTLKYDSK 248
            ....:.:|     ||  .||:|..|:|...:.:|||:.     |.:.|              |..
Mouse   176 RPFASTFV-----GG--ELYTGLTADFLGREAMIFRSGGPRPALRSDS--------------DQS 219

  Fly   249 WLDKPNFVGSFDI-------GEYVYFFFRETAVEYI-NCGKAVYSRIARVCKKDVGGKNLLAHNW 305
            .|.:|.||.:..|       .:.|||||.||..... ..|....||:.|||..|.||:.:|.:.|
Mouse   220 LLHEPRFVMAARIPDNSDRDDDKVYFFFSETVPSPDGGPGHVTISRVGRVCVNDAGGQRVLVNKW 284

  Fly   306 ATYLKARLNCSISGE--FPFYFNEIQSVYQL--PSDKS-RFFATFTTSTNGLIGSAVCSFHINEI 365
            :|:|||||.||:.|.  ...:|::::.|:.|  .:.|| ..:|.|:|.:....|.|||.:|:.:|
Mouse   285 STFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMVDI 349

  Fly   366 QAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTC-----------VNDTSNLPDTVLNFIRSHPL 419
            ...|||.|..:......|.| ...:||.||||.|           ...|.:.||.||.|:|.|||
Mouse   350 WEVFNGPFAHRDGPQHQWGP-YGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRDHPL 413

  Fly   420 MDKAVNHEHNNPVYYKRDLV--FTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNG--- 479
            |.:.|......||..|..|.  ..::|||  |::..:..|.|.::||:.|.:.|::.....|
Mouse   414 MFQPVRPRRGRPVLVKTHLAQRLRQIVVD--RVEAEDGTYDVIFLGTDSGSVLKVIALQGGGLTE 476

  Fly   480 --ESLSKLLDIFEVAPNEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRC--VRDPY 540
              |.:.:.|.:|:|.  ..|..||||..|::||:|:...:.::.|..|......|..|  .||||
Mouse   477 PEEVVLEELQVFKVP--TPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPY 539

  Fly   541 CGWDKEANTCRPY----------ELDL------LQDVANETSDICDSSVLKKKIVVTYGQSVHLG 589
            |.||..|  |..|          ..|:      :|.:....|....:|.|..::..|...|..|.
Mouse   540 CAWDGTA--CARYRPSSGKRRFRRQDIRHGNPAVQCLGQGQSQNKAASGLMTRVFGTEHNSTFLE 602

  Fly   590 CFVKIPEVLKNEQVTWY-HHSKDKGRYEIRYSPTKYIETTER------GLVVVSVNEADGGRYDC 647
            |..|.|:.    .|.|: ....|||        |..::|.||      ||:...::..|.|.|.|
Mouse   603 CLPKSPQA----AVRWFLQRPGDKG--------TDQVKTDERVVQTAQGLLFRRLSRHDAGNYTC 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	153/497 (31%)
		Ig_Semaphorin_C	573..664	CDD:143180	21/81 (26%)
Sema3g	NP_001020550.1	Sema	49..522	CDD:301699	155/501 (31%)
		PSI	521..567	CDD:214655	14/47 (30%)
		Ig_Semaphorin_classIII	591..676	CDD:143279	20/76 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910