Protein Alignment Sema2a and smp-2

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_491197.3
• Gene: smp-2 / 183905
• WormBaseID: WBGene00004890
• Length: 649
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 133/565 - (23%)
• Similarity: 245/565 - (43%)
• Gaps: 132/565 - (23%)

  Fly    82 VGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDV--VSCVSKGKSQIFDCKNHVRVIQSMDQGDR 144
            :|..:.|:.:::.::      .::...|.|..|.  .:|.:..::.. .|:|.:|....: ..|.
 Worm    59 LGGRNHVYNISISSM------LEIARYEWTSSDEARTNCAAISQTPA-SCENFIRTYFEL-TNDT 115

  Fly   145 LYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLD-NSTAIYVENGNPGGLPGLY 208
            |.:|||:|..| ....:......|: ..:..||:       .|:| :|||.::.:..     .:.
 Worm   116 LILCGTHALQP-TCAEFRKGNAKPQ-RLISAVGM-------SPIDADSTAPFIRSNE-----NII 166

  Fly   209 SGTNAEFTKADTVIFRTDLYNTSAKRLEYK-FKRTLKYDSKWLDKPNFVGSFDIGEYVYFFFRET 272
            :...||.:.::.::.|.::.. ..|.:|.. ..||.:..|.: ::.||:....:.:.|.|||.|:
 Worm   167 TVNVAELSSSEPLLVRRNVIK-MWKGIENDVILRTPRGLSSF-EQANFLSMHKVKKEVLFFFSES 229

  Fly   273 AVEYINCGKAVYSRIARVCKKDVGGKNLLAHN--WATYLKARLNCSI--SGEFPFYFNEIQSVYQ 333
            .:|...||....:|:.|||:.|.||:  |::|  |::|.|||:.|||  :....||||:...|.:
 Worm   230 PMETEGCGLHKVARVGRVCEDDPGGR--LSYNKEWSSYEKARIECSIEETDTDTFYFNQFAGVAE 292

  Fly   334 LPSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGT 398
            .|:.   |:..|.:...|:..||:|.:....|..:|...:||.:                  |.|
 Worm   293 SPTS---FYGAFRSQLAGIGASAICKYSKKVISGSFASGYKEST------------------PDT 336

  Fly   399 C--VNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVY--YKRDLVFTKLVVDKIRIDILNQEYIV 459
            |  .||...     |:.||..||:.:.::   .||:|  :.:|. |..::..:...|:.|:.|.:
 Worm   337 CSRANDIEE-----LSRIRLKPLIKQKIS---ANPIYIFHGKDR-FVHVLAQEDTRDLSNRAYDI 392

  Fly   460 YYVGTNLGRIYKIV-----QYYRNGESL------SKLLDIFEVAPNEAIQVMEISQTRKSLYIGT 513
            .||.||||.|.|||     :..|:..:|      ||::|:...:.|..          :.|.:.|
 Worm   393 LYVATNLGNILKIVVPSTDKTGRHAVTLKVLPTNSKIVDMSLYSKNNL----------EELIVIT 447

  Fly   514 DHRIKQIDLAMCNRRYDNCFRCVR--DPYCGW-----------------DKEANTC--------R 551
            :..:.::..|.|:.. .||..|:.  ||:|.|                 .:::.||        :
 Worm   448 EQSVLKVPTATCHLA-SNCAECLAHGDPHCAWADGVDCIDIRTDQRKSASQDSGTCDVVSFENHK 511

  Fly   552 PYELDLLQDVANETSDI-------------CDSSVLKKKIVVTYG 583
            |..:..|::  .|::.|             |.:.|::|:||:|.|
 Worm   512 PVMIAPLKN--KESAKIPVCLCETEKQKKPCATEVIQKEIVLTGG 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	111/463 (24%)
		Ig_Semaphorin_C	573..664	CDD:143180	6/11 (55%)
smp-2	NP_491197.3	Sema	47..429	CDD:214747	106/425 (25%)
		Sema	<390..478	CDD:387663	27/98 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910