Protein Alignment Sema2a and smp-1

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001379344.1
• Gene: smp-1 / 173351
• WormBaseID: WBGene00004889
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 185/608 - (30%)
• Similarity: 304/608 - (50%)
• Gaps: 101/608 - (16%)

  Fly    13 LLLLCSSVSETAADYENTWNFYYERPCCTGNDQG-NNNYGKHG-----ADHVREFNCGKLYYRTF 71
            ||||.:.|..:.|......|.   ||....|..| .:.:|..|     :||.      ||
 Worm     7 LLLLFNVVRSSEAITGGVVNL---RPKQIINSVGIGDRFGGIGTSSDESDHF------KL----- 57

  Fly    72 HMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCKNHVRVI 136
             :..|.|:|.|||.:.|:.::|..:|.::    .|:.:|..:.:..|:.||||:. ||:|::||:
 Worm    58 -LAADGDSLLVGARNAVYNLSLSTLSVNH----KIDWKPPAEHIEECIMKGKSKT-DCQNYIRVL 116

  Fly   137 QSMDQGDRLYVCGTNAHNPK--DYVIYANLTHLPRSEYVIGV-------GLGIAKCPYDPLDNST 192
            .....|..| ||||:|.:||  :|.:         :|:  |:       |.||:  ||||..||:
 Worm   117 ARKSAGVSL-VCGTHAFSPKCREYTV---------TEF--GIRNTRQFDGQGIS--PYDPKHNSS 167

  Fly   193 AIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVG 257
            |:||...|.     |:..|..:|...|.:|:|..:..|.:.:..... ||..||::.|:.||||.
 Worm   168 ALYVPGTNQ-----LFVATVTDFVGNDALIYRKTIDETPSSKSAANI-RTQSYDARVLNAPNFVA 226

  Fly   258 SFDIGEYVYFFFRETAVEYI--NCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSI-SG 319
            :|...|:|||:|||.|.|.|  |....:|:|:|||||.|.||.......|.:|||||||||: ||
 Worm   227 TFAYKEHVYFWFREIASEAIDNNEEPQIYARVARVCKNDKGGARPANERWTSYLKARLNCSLPSG 291

  Fly   320 EFPFYFNEIQSVYQLPSDKSR----FFATFTTSTNGLIGSAVCSFHINEIQAAF-NGKFKEQSSS 379
            ..||||||:::|.. |.|...    .:..|:|..:.:..||||.|.:.:|:..| ||.||.|:::
 Worm   292 SSPFYFNELKAVSD-PIDAGNNNHVVYTVFSTPDSDVRMSAVCKFSMKKIREEFDNGTFKHQNNA 355

  Fly   380 NSAWLPVLNSRVPEPRPGTCVNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLV 444
            .|.|:....:.||:||||:|..|::.||:..::||..|||:.:.:            ..|...|:
 Worm   356 QSMWMAFNRNEVPKPRPGSCSPDSTKLPENTVSFILHHPLLHRPI------------PSVAAPLL 408

  Fly   445 V------DKIRIDIL-------NQEYIVYYVGTNLGRIYKIVQYYRNGESLSKLLDIFEVAPNEA 496
            |      |..:|.:|       ...|.:.::||:.|::.|:|:...|. ::.:...:|:    ..
 Worm   409 VEGADRADLTQITVLPRVRAVGGHNYDILFIGTSDGKVLKVVEVDGNA-TVIQSATVFQ----RG 468

  Fly   497 IQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRCV--RDPYCGWDKEANTC---RPYELD 556
            :.::.:..|::|:.|.:...|..:.:..|.:: .:|.:||  :||:|.||.....|   ..:..|
 Worm   469 VPIVNLLTTKESVVIVSADEIASLPVHNCAQQ-TSCSKCVQLQDPHCAWDSSIARCVHGGSWTGD 532

  Fly   557 -LLQDVANETSDICDSSVLKKKI 578
             .:|::....|:.|...::.:::
 Worm   533 QFIQNMVFGQSEQCPEGIIVREV 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	155/486 (32%)
		Ig_Semaphorin_C	573..664	CDD:143180	0/6 (0%)
smp-1	NP_001379344.1	Sema_1A	49..497	CDD:200498	158/502 (31%)
		PSI	496..547	CDD:214655	13/51 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007625
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010