Protein Alignment Sema2a and LOC1277221

DIOPT Version :10

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_061506710.1
• Gene: LOC1277221 / 1277221
• VectorBaseID: AGAMI1_011129
• Length: 741
• Species: Anopheles gambiae
• Alignment Length: 725
• Identity: 578/725 - (79%)
• Similarity: 651/725 - (89%)
• Gaps: 12/725 - (1%)

  Fly     9 LLALLLLLCSSVSETAADYENTWNFYYERPCCTGNDQGN--------NNYGKHGADHVREFNCGK 65
            :|.:..:|...:...|.|||||||||||:||| |:.|.|        .::.:|..||||||.|||
Mosquito    20 VLTVAFVLLQLLRPGAGDYENTWNFYYEQPCC-GSGQSNVGGISINGQHHLRHHRDHVREFQCGK 83

  Fly    66 LYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVVSCVSKGKSQIFDCK 130
            .|||||:::|:|||||||||||||::||:|:|.::|.||.|.|:||..|:.:|||||||::||||
Mosquito    84 FYYRTFYLDEERDTLYVGAMDRVFKLNLKNVSMTSCERDTIVLDPTSSDIRNCVSKGKSEMFDCK 148

  Fly   131 NHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTAIY 195
            ||:||||.||.|:|||:||||||||||.|||:|||||||||||.|:|||||||||||.|||||||
Mosquito   149 NHIRVIQPMDSGNRLYICGTNAHNPKDLVIYSNLTHLPRSEYVPGIGLGIAKCPYDPYDNSTAIY 213

  Fly   196 VENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVGSFD 260
            ||.||||.||.|||||||||||||||||||||||.:..:..:.||||||||||||||||||||||
Mosquito   214 VEQGNPGDLPALYSGTNAEFTKADTVIFRTDLYNMTTGKKVFNFKRTLKYDSKWLDKPNFVGSFD 278

  Fly   261 IGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNLLAHNWATYLKARLNCSISGEFPFYF 325
            |||:||||||||||||||||||||||:|||||||.||||:|..|||||||||:||||||||||||
Mosquito   279 IGEHVYFFFRETAVEYINCGKAVYSRVARVCKKDTGGKNILNQNWATYLKARINCSISGEFPFYF 343

  Fly   326 NEIQSVYQLPSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWLPVLNSR 390
            ||||.|||||:||::|:||||||||||:|||||||.||||..||.||||||:||||||||||||:
Mosquito   344 NEIQDVYQLPTDKTKFYATFTTSTNGLVGSAVCSFDINEIHGAFAGKFKEQASSNSAWLPVLNSK 408

  Fly   391 VPEPRPGTCVNDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQ 455
            :|||||||||||||.|||:|||||||||||||||||||||||||||||||||||||||:|:||:|
Mosquito   409 IPEPRPGTCVNDTSTLPDSVLNFIRSHPLMDKAVNHEHNNPVYYKRDLVFTKLVVDKIKIEILSQ 473

  Fly   456 EYIVYYVGTNLGRIYKIVQYYRNGESLSKLLDIFEVAPNEAIQVMEISQTRKSLYIGTDHRIKQI 520
            ||.|:|:|||.|||||||||.|||||.||||||||:|.||||||||:||.|||||:.||:|||||
Mosquito   474 EYTVFYIGTNAGRIYKIVQYLRNGESKSKLLDIFEIAQNEAIQVMELSQKRKSLYVATDYRIKQI 538

  Fly   521 DLAMCNRRYDNCFRCVRDPYCGWDKEANTCRPYELDLLQDVANETSDICDSSVLKKKIVVTYGQS 585
            ||||||||||||||||:||||||||:.:||:|||..|||||.|||.||||:|||||||:||||||
Mosquito   539 DLAMCNRRYDNCFRCVKDPYCGWDKDTSTCKPYEPGLLQDVGNETYDICDTSVLKKKIIVTYGQS 603

  Fly   586 VHLGCFVKIPEVLKNEQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDCHLG 650
            |||||||||||:||::.||||||||:||||||:|:||||||||||||||:|||||||||||||||
Mosquito   604 VHLGCFVKIPEILKDQTVTWYHHSKEKGRYEIKYNPTKYIETTERGLVVISVNEADGGRYDCHLG 668

  Fly   651 GSLLCSYNITVDAHRCTPPNKSNDYQKIYSDWCHEFEKYKTAMKSWEKKQAQCSTRQNFSSNQHP 715
            |||||||||||||||||||||:||||||||||||||||||:|||:||||||||| |||: |||||
Mosquito   669 GSLLCSYNITVDAHRCTPPNKTNDYQKIYSDWCHEFEKYKSAMKTWEKKQAQCS-RQNY-SNQHP 731

  Fly   716 NEIF-RKPNV 724
            |::| |.|||
Mosquito   732 NDVFARTPNV 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	373/456 (82%)
		PSI	527..>550	CDD:396154	18/22 (82%)
		Ig_Semaphorin_C	573..668	CDD:409368	85/94 (90%)
		Ig strand A	573..579	CDD:409368	5/5 (100%)
		Ig strand B	583..591	CDD:409368	7/7 (100%)
		Ig strand C	601..607	CDD:409368	3/5 (60%)
		Ig strand C'	609..612	CDD:409368	2/2 (100%)
		Ig strand D	622..626	CDD:409368	3/3 (100%)
		Ig strand E	630..637	CDD:409368	5/6 (83%)
		Ig strand F	643..652	CDD:409368	8/8 (100%)
		Ig strand G	655..668	CDD:409368	12/12 (100%)
LOC1277221	XP_061506710.1	None