Protein Alignment Sema2a and sema6c

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_002937315.2
• Gene: sema6c / 100486277
• XenbaseID: XB-GENE-989787
• Length: 1043
• Species: Xenopus tropicalis
• Alignment Length: 691
• Identity: 206/691 - (29%)
• Similarity: 321/691 - (46%)
• Gaps: 144/691 - (20%)

  Fly     9 LLALLLLLCSSVSETAA-----------DYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFN 62
            |..:|||:|:.:|....           :...|.::.:.|...:.:|..               :
 Frog     6 LRGVLLLVCTYLSSALVFPKDLTPIRIIETLTTSSYPWFRGLASDDDTA---------------H 55

  Fly    63 CGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTR------DDVVSCVSK 121
            .|..:.:...:|:   ||:|.|.|.|:.::|:....:        :.|.:      .|:.:|..:
 Frog    56 LGLDFQKMLKLNQ---TLFVAARDHVYAIDLRRAKEA--------IIPDKYVTWKTQDMENCAMR 109

  Fly   122 GKSQIFDCKNHVRV-IQSMDQGDRLYVCGTNAHNP--KDYVIYANLTHLPRSEYVIGVGLGIAKC 183
            ||.: .:|.|:::| :...||  .|..||||:.||  :.|.|  ........|:     .|.|:|
 Frog   110 GKLR-DECYNYIKVLVPKNDQ--TLVACGTNSFNPMCRSYKI--KTLEQEGEEF-----NGQARC 164

  Fly   184 PYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSK 248
            |:|....:.|::.: ||      |||.|.|:|..:|.||:|: |...|      ...||:|||||
 Frog   165 PFDAKQANVALFAD-GN------LYSATMADFQASDAVIYRS-LGEKS------PVLRTVKYDSK 215

  Fly   249 WLDKPNFVGSFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGK-NLLAHNWATYLKAR 312
            ||.:|:|:.:.:.|.||||||||.::||...||..:||:.||||.|:||. .:|...|.::||||
 Frog   216 WLREPHFIHAVEYGNYVYFFFREISMEYTTIGKVTFSRVGRVCKNDMGGSPRVLEKYWTSFLKAR 280

  Fly   313 LNCSISGEFPFYFNEIQSVYQLPSDKSR--FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKE 375
            ||||:.|:..|||:.:|||..:.:..:|  ....|.|..|.:.||.||::::::|:..|||||||
 Frog   281 LNCSVPGDSFFYFDVLQSVSDILTINNRPAVIGVFGTQANSITGSGVCAYYMDDIEKVFNGKFKE 345

  Fly   376 QSSSNSAWLPVLNSRVPEPRPGTCVN-------DTSN-LPDTVLNFIRSHPLMDKAVNHEHNNPV 432
            |.::.|||.|:...:||.||||.|..       .||| .||..|:||:|:||:|:||......|.
 Frog   346 QKTTESAWTPIPEDKVPTPRPGCCAGYGKAATYKTSNEFPDETLSFIKSYPLLDEAVLSITETPW 410

  Fly   433 YYKRDLVF--TKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNGESLSKLL--DIFEVAP 493
            :.|....|  |.|..|.......|  |.|.::|:..|::.|::.......::..||  ||....|
 Frog   411 FTKTTSRFKLTHLAADTSAGPYGN--YTVLFLGSEDGKVLKVLSGTTENSTVETLLLEDINVYNP 473

  Fly   494 --------NEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFR-CV--RDPYCGWDKEA 547
                    :..|..:::.:...:|::.....|.::.|:.| ..|..|.| |:  |||||.|.| :
 Frog   474 AKCNVKKEDRRILGLQLDRENHALFVAFSSCIIRVPLSRC-ELYGTCRRSCLASRDPYCVWLK-S 536

  Fly   548 NTCRPYELDL----------------LQD-------VANE----------TSDICDSSVLKKKIV 579
            ..|..|..|:                .||       |.||          :.||..:||.....|
 Frog   537 GACASYRNDIRGSFEQDIEQSKNWGNCQDVVTSSGSVGNEGDSAYGKAPPSGDIAIASVASLGHV 601

  Fly   580 VTYGQSVHLGCFVKIPEVLKN--EQVTWYHHSKDKG-RYEI 617
            ...|.|.        |.|..:  .|::.:|..|.:| |.|:
 Frog   602 TRLGYSP--------PGVTSDGYYQLSAWHTLKTQGVRQEV 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	160/488 (33%)
		Ig_Semaphorin_C	573..664	CDD:143180	12/48 (25%)
sema6c	XP_002937315.2	Sema_6E	50..511	CDD:200531	162/512 (32%)
		PSI	512..>533	CDD:214655	10/21 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	283	1.000	Inparanoid score	I2804
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060