Protein Alignment Sema2a and sema4c

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_004912631.1
• Gene: sema4c / 100486259
• XenbaseID: XB-GENE-856519
• Length: 837
• Species: Xenopus tropicalis
• Alignment Length: 655
• Identity: 197/655 - (30%)
• Similarity: 309/655 - (47%)
• Gaps: 85/655 - (12%)

  Fly    53 HGADHVRE-FNCGKLYYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTRDDVV 116
            ||...||: :..|.....|..::|||..|||||.:.:|.::|.||...  .|..|..:...|...
 Frog    33 HGVSVVRQSWRNGVSQVMTLTLDEDRGALYVGAREVIFSLDLSNIGKE--LRPPIIWQAPADKKA 95

  Fly   117 SCVSKGKSQIFDCKNHVRVIQSMDQGDRLYVCGTNAHNPK-DYVIYANLTHLPRSEYVIGVGLGI 180
            .|..||||...:|.|::|.::..:| ..|..|||.|..|| .|:..:..| |.......|.|
 Frog    96 ECAQKGKSNQTECFNYIRFLEEYNQ-THLITCGTYAFQPKCAYIALSGFT-LDADNLEEGKG--- 155

  Fly   181 AKCPYDPLDNSTAIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKY 245
             |.||||....|.:.::.       .|||.|...|...:.||.|....:...|         .:|
 Frog   156 -KVPYDPAKGYTGLILDG-------ALYSATMNNFLGTEPVIMRIVGQHNIMK---------TEY 203

  Fly   246 DSKWLDKPNFVGS--------FDIG--EYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGGKNL 300
            .:.||::||||.|        .:||  :.:|:||.|.|:||....:.|.||:||:||.|:||...
 Frog   204 LASWLNEPNFVSSAHMPESVGSEIGDDDKIYYFFTERALEYDCSSEQVVSRVARICKGDLGGART 268

  Fly   301 LAHNWATYLKARLNCSISGEFPFYFNEIQSVYQLPSDK---SRFFATFTTSTNGLIGSAVCSFHI 362
            |...|.::|||||.|||. |....||.::||::|.:::   ::|||.|.........||||.:.|
 Frog   269 LQRKWTSFLKARLLCSIP-ELQLNFNLLKSVFKLEAEEWRSTQFFAAFQARWGDSPVSAVCQYSI 332

  Fly   363 NEIQAAFNGKFKEQSSSNSAWLPVLNSRVPEPRPGTCVND---------TSNLPDTVLNFIRSHP 418
            ::||..|:|.:||....:..|....:| ||.||||:|:.:         :..|||..|||::.||
 Frog   333 HDIQKVFDGPYKEYREQSQKWGRYSDS-VPSPRPGSCITNWHRNHGVYSSLELPDNTLNFVKKHP 396

  Fly   419 LMDKAVNHEHNNPVYYKRDLVFTKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNGESLS 483
            |||..|......|:..:|.:.||.:.|.: .:.:..:.|.|.::||:.|.:.|.|.:   |.::.
 Frog   397 LMDDTVMPSQGRPLLVRRGINFTTIAVQR-TLGLDKEPYDVLFIGTDNGWVNKAVSF---GSTVH 457

  Fly   484 KL--LDIFEVAPNEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFRCV--RDPYCGWD 544
            .:  |.:|:  .:..:..:.:|..:..||:|:...:.|:..|.|: :|.:|..|:  |||||.|:
 Frog   458 IIEELQVFD--KSYPVNSLAVSSRKSLLYVGSQSGLVQLPFADCS-KYRSCADCILARDPYCAWN 519

  Fly   545 KEANTC----RPYELDLLQDVANETSDICDSS-------VLKKKIVVTYGQSVHLGCFVKIPEVL 598
            ...:.|    ..:...||||:.:..:.:|:..       ...|.|.:..|.:|.|.|     ::.
 Frog   520 VNISRCVRADEQHRSVLLQDIQDSDTSVCEVQNMNAAVRYFSKNITIGIGTNVVLPC-----QLS 579

  Fly   599 KN-EQVTWYHHSKDKGRYEIRYSPTKYIETTERGLVVVSVNEADGGRYDC--HLGGSLLCS--YN 658
            .| .:..|....:|.|..:   ..:...:.|.:.||::.|.....|.|.|  ...|:.|.|  |.
 Frog   580 SNLAEPIWTFDGQDMGSDQ---DDSVLFDATLQALVILGVGTHHSGSYVCFSEEQGTRLTSENYQ 641

  Fly   659 ITVDA 663
            :||.|
 Frog   642 LTVVA 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	151/481 (31%)
		Ig_Semaphorin_C	573..664	CDD:143180	24/96 (25%)
sema4c	XP_004912631.1	Sema_4C	38..497	CDD:200519	154/490 (31%)
		PSI	498..>530	CDD:214655	11/32 (34%)
		Ig	562..647	CDD:386229	24/93 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010