Protein Alignment Sema2a and sema6bb

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: XP_021327709.1
• Gene: sema6bb / 100148883
• ZFINID: ZDB-GENE-081105-129
• Length: 874
• Species: Danio rerio
• Alignment Length: 636
• Identity: 204/636 - (32%)
• Similarity: 309/636 - (48%)
• Gaps: 111/636 - (17%)

  Fly     9 LLALLLLLCSSVSE-------TAADYENTWNFYYERPCCTGNDQGNNNYGKHGADHVREFNCGKL 66
            |..||.|:|:...|       ...|....:..:..||        :::..:|...|::
Zfish    11 LFWLLRLVCAVFPEEPGPLNFVRTDVVRKYPVFLGRP--------HHSTLRHEPLHIQ------- 60

  Fly    67 YYRTFHMNEDRDTLYVGAMDRVFRVNLQNISSSNC----NRDVINLEPTRDDVVSCVSKGKSQIF 127
              |...:|.   |||:||.|.:|||.|.|:.....    .|   ..|..::|:..|..|||.: .
Zfish    61 --RILQVNR---TLYIGARDDLFRVELDNVVGEEMFYSKKR---TWESNKNDIRICRMKGKHE-D 116

  Fly   128 DCKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNST 192
            :|:|:::|:.|...|  |::|||||.||    :.||.|. ...|.|.....|:|:|||||...:.
Zfish   117 ECRNYMKVLLSRQGG--LFICGTNAFNP----LCANYTG-DTLEMVGETVSGMARCPYDPKHANV 174

  Fly   193 AIYVENGNPGGLPGLYSGTNAEFTKADTVIFRTDLYNTSAKRLEYKFKRTLKYDSKWLDKPNFVG 257
            |::.|.       .||:.|..:|...|.||:|:...|.:.        ||:|:||||..:|.||.
Zfish   175 ALFAER-------NLYTATVTDFLAIDAVIYRSLGDNPAL--------RTVKHDSKWFREPYFVS 224

  Fly   258 SFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGG-KNLLAHNWATYLKARLNCSISGEF 321
            :.:.|.:|||||||.|:|:....|.|.||:|||||.|.|| :.:|...|.::|||||||||.|:.
Zfish   225 AVEWGPHVYFFFREMAMEFNYLEKVVVSRVARVCKADQGGSQRVLEKQWTSFLKARLNCSIPGDS 289

  Fly   322 PFYFNEIQSVYQLPSDKSR--FFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSSNSAWL 384
            .||||.:.|...:.....|  ..|.|:|.:|.:.|||||:|.:.::...|:|:||||.|..|.|.
Zfish   290 HFYFNLLHSTSPIIRMHGRDIILAVFSTPSNSIPGSAVCAFDMEQLAGVFDGRFKEQKSPESIWT 354

  Fly   385 PVLNSRVPEPRPGTCV------NDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKRDLV---F 440
            ||.:..:|:||||.|.      |.:::.||.:|.|:::|||||:||......| :..|.:|   .
Zfish   355 PVPDEALPKPRPGGCAVQGSKFNSSNSFPDDMLTFVKTHPLMDEAVPSLGQRP-WIVRTMVRYQL 418

  Fly   441 TKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIVQYYRNGESLSK---LLDIFE-VAPN------- 494
            .|:|||.......||  .|.::|::.|.|.|.:.......:::.   .|:.|| ..|:
Zfish   419 NKMVVDTNAGPYGNQ--TVLFLGSSRGTILKFLVTPNRDNTVTNNNVFLEEFEGYNPDRCGTDSP 481

  Fly   495 EAIQVMEISQTR--KSLYIGTDHRIKQIDLAMCNRRYDNCFR-CV--RDPYCGWDK-------EA 547
            :|.|::.::..|  .||.:.....:.::.:|.| :.|..|.: |:  |||||||..       .|
Zfish   482 QARQLLSLTLDRISHSLLLTFPSCVIKVPVARC-QLYSACMKNCIASRDPYCGWTTGDICSFLRA 545

  Fly   548 NTCRPYELDLLQDVANETSDICDSSVLKKKIVVTYGQSVHLGCFVKIPEVL 598
            .|..|:|.|:.|...:...| ||..              ..|.|::.|:.|
Zfish   546 GTRLPFEQDVEQGNTSHLGD-CDGP--------------QQGRFIEEPDGL 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	168/485 (35%)
		Ig_Semaphorin_C	573..664	CDD:143180	4/26 (15%)
sema6bb	XP_021327709.1	Sema	49..512	CDD:326631	170/503 (34%)
		PSI	513..571	CDD:214655	20/73 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010