Protein Alignment Sema2a and sema6d

DIOPT Version :9

• Sequence 1: NP_477507.1
• Gene: Sema2a / 36846
• FlyBaseID: FBgn0011260
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_001120152.1
• Gene: sema6d / 100145190
• XenbaseID: XB-GENE-967070
• Length: 1084
• Species: Xenopus tropicalis
• Alignment Length: 679
• Identity: 208/679 - (30%)
• Similarity: 321/679 - (47%)
• Gaps: 144/679 - (21%)

  Fly    13 LLLLCSSVSETA--ADYE--NTWNFYYER--PCCTGNDQGNNNYGKHGADHVREFNCGKLYYRTF 71
            |||..|:|...:  .|.|  |..:::|.|  |...|...||:      :.|..:|..
 Frog    11 LLLTVSTVCAVSFPEDDEPINVVDYHYSRQYPVFRGRPSGND------SQHSLDFQL-------- 61

  Fly    72 HMNEDRDTLYVGAMDRVFRVNLQNISSSNCNRDVINLEPTR--------DDVVSCVSKGKSQIFD 128
             |.:.||||||...|:|:.:||..:..:       .:.|:|        .|..:|..|||.: .:
 Frog    62 -MLKIRDTLYVAGRDQVYAINLNEVPKT-------EVTPSRRLTWRSGQADRKNCAMKGKHK-DE 117

  Fly   129 CKNHVRVIQSMDQGDRLYVCGTNAHNPKDYVIYANLTHLPRSEYVIGVGLGIAKCPYDPLDNSTA 193
            |.|:::|....:. :.::||||||.||.......|.......|.     .|:|:||:|....:.|
 Frog   118 CHNYIKVFVPRND-EMVFVCGTNAFNPMCRYYRLNTFDYDGEEI-----SGLARCPFDARQTNVA 176

  Fly   194 IYVENGNPGGLPGLYSGTNAEFTKADTVIFRT--DLYNTSAKRLEYKFKRTLKYDSKWLDKPNFV 256
            ::.:.       .|||.|.|:|..:|.||:|:  |.:..          ||:|||||||.:|:|:
 Frog   177 LFADG-------KLYSATMADFQASDAVIYRSMGDGFAL----------RTIKYDSKWLKEPHFL 224

  Fly   257 GSFDIGEYVYFFFRETAVEYINCGKAVYSRIARVCKKDVGG-KNLLAHNWATYLKARLNCSISGE 320
            .:.:.|.|:||||||.|||:.|.||||:||:||:||.|:|| :.:|..:|.:::|||||||:.|:
 Frog   225 HAIEYGNYIYFFFREIAVEHNNLGKAVHSRVARICKNDLGGSQRVLEKHWTSFVKARLNCSVPGD 289

  Fly   321 FPFYFNEIQSVYQ------LPSDKSRFFATFTTSTNGLIGSAVCSFHINEIQAAFNGKFKEQSSS 379
            ..|||:.:||:..      :|:    ....|||..|.:.|||||:|.:::|:..|.|:||||.:.
 Frog   290 SFFYFDVLQSITDIIEINGIPT----VVGVFTTQLNSIPGSAVCAFTMDDIEKVFRGRFKEQKTP 350

  Fly   380 NSAWLPVLNSRVPEPRPGTCV--------NDTSNLPDTVLNFIRSHPLMDKAVNHEHNNPVYYKR 436
            :|.|..|...|||:||||.|.        ..::..||..|:||:||||||.|:......|.:.|.
 Frog   351 DSVWTAVPEDRVPKPRPGCCARHGYGEGYRSSTEFPDETLSFIKSHPLMDSAIPSIIEEPWFTKT 415

  Fly   437 DLVF--TKLVVDKIRIDILNQEYIVYYVGTNLGRIYKIV----QYYRNGESLSKLLDIFEVA--- 492
            .:.:  |.:.||.:....||  |.|.:||:..|.:.||:    .:..|...|.:.:|.:..|
 Frog   416 RVRYRLTAVAVDHLAGPYLN--YTVMFVGSEAGVVLKILAKTNPFSLNDSVLLEEIDAYNRAKCS 478

  Fly   493 ----PNEAIQVMEISQTRKSLYIGTDHRIKQIDLAMCNRRYDNCFR-CV--RDPYCGW--DKEAN 548
                .:..:..:::.:...:|::.....|.::.|:.| .||.:|.: |:  |||||||  .:...
 Frog   479 GNSEEDRKVISLQMDRDHHALFVAFSGCIVRLPLSRC-ERYGSCKKSCIGARDPYCGWLNHESCG 542

  Fly   549 TCRP-----YELDLLQDVANETSDICDSSVLKKKIVVTYGQSVHLG-CFVKIPEVLKNEQVTWYH 607
            ..:|     ||.|                       |.||.:|.|| |...:|.....:
 Frog   543 RVKPGMFFGYEQD-----------------------VEYGNTVQLGDCHDILPTATTPD------ 578

  Fly   608 HSKDKGRYEIRYSPTKYIETTERGLVVVS 636
                   |:|...||..||.....:...|
 Frog   579 -------YKIFGDPTSDIEVPSTSVTTTS 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema2a	NP_477507.1	Sema_2A	66..523	CDD:200499	160/494 (32%)
		Ig_Semaphorin_C	573..664	CDD:143180	15/65 (23%)
sema6d	NP_001120152.1	Sema_6D	49..513	CDD:200530	164/515 (32%)
		PSI	514..>543	CDD:396154	12/29 (41%)
		ARG80	<829..1080	CDD:227400

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	283	1.000	Inparanoid score	I2804
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060