DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment S-Lap8 and AT4G30910

DIOPT Version :9

Sequence 1:	NP_611132.1	Gene:	S-Lap8 / 36844	FlyBaseID:	FBgn0034132	Length:	534	Species:	Drosophila melanogaster
Sequence 2:	NP_001328632.1	Gene:	AT4G30910 / 829215	AraportID:	AT4G30910	Length:	604	Species:	Arabidopsis thaliana

Alignment Length:	610	Identity:	139/610 - (22%)
Similarity:	254/610 - (41%)	Gaps:	127/610 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RSQMISSLR--------------------RSTLGLFRC----HKALIFARIPAFQQVRCKSEDGS 43
            |.|::|.||                    .:||||.:.    |..:.|:.    :::......|.
plant    33 RFQLLSRLRVSFAITPLYCSSKATAHTIAHATLGLTQANSVDHPKISFSG----KEIDVTEWKGD 93

  Fly    44 CNTCNLQGVVVGLYAKD--GDKGLKL-SPGGEKFDDRVGGKITELIKESGLNGELGVGRLYQNID 105
            .       :.||:..||  .|...|. :|..:|.|..:||.:.::..|...:|:.|...:.:...
plant    94 I-------LAVGVTEKDMAKDANSKFENPILKKLDAHLGGLLADVSAEEDFSGKPGQSTVLRLPG 151

  Fly   106 KEYWAVAVVGLGKEGAGFNAEEVIDEGMENVRVCAAVGARALQLQGCTTCHVDGMEYPEQA---- 166
            .....|.::||||..:..:|.:.:.|.:       |..|:|.|.............:.:::
plant   152 LGSKRVGLIGLGKSASTPSAFQSLGEAV-------AAAAKASQASSVAVVLASSESFSDESKLSS 209

  Fly   167 ----AEGAAMAVW---RYNVNKRKKNRIAI--------PKLELYGSTDQDAWTRGLFKAESQN-- 214
                |.|..:.::   ||....:|.:..::        |:||           ..|..||..:
plant   210 ASDIASGTVLGLFEDSRYKSESKKPSLKSVVFIGFGTGPELE-----------NKLKYAEHVSYG 263

  Fly   215 --LARRLSDTPANQMTPSIFAQ--ATVDALCPCGVSVEVRSMDWIETQNLNSFLMVAKGSCEPPI 275
              ..:.|.::|||.::|::.|:  :.:.::....::..:...:..:...:.|:|.||..|..||.
plant   264 VIFTKELVNSPANVLSPAVLAEEASNLASMYSNVMTANILKEEQCKELKMGSYLAVAAASANPPH 328

  Fly   276 ILEVSYCGTS-PEERPILMLGKGLTFNSGG--LCLHPKRGMDEYRGAVSGAAVCVAAIRAAAALS 337
            .:.:.|..:| |.:..:.::||||||:|||  :.:.|:..::..:..|.|:|..:.|.:|...:.
plant   329 FIHLIYKPSSGPVKTKLALVGKGLTFDSGGYNIKIGPELIIELMKIDVGGSAAVLGAAKAIGEIK 393

  Fly   338 LP-INVSAVLPLCENMPSGMATKPGDVVTLLNGKT-----------------------MRIKDIS 378
            .| :.|..::..||||.||...:||||:|..||||                       :::.|..
plant   394 PPGVEVHFIVAACENMISGTGMRPGDVITASNGKTIEVSLHRFHMNSASKGSSFPLLVLQVNDTD 458

  Fly   379 LAGTVLLADPLLYAQSTFKPKLVVEVGSMASGIRKGLGASATGLWTNNSFLWKNFQKAGALTGDR 443
            ..|.:.|||.|:||.:....| :|::.::...|...||.|..|::|.:..|.|....|...:|::
plant   459 SEGRLTLADALVYACNQGVDK-IVDIATLTGEIIVALGPSMAGMYTASDELAKEVIAASQRSGEK 522

  Fly   444 LWRMPL----WRYFRKLVAPRASYDICSTGEGHASSCLAAAILYELVPCS-DWVHLDTHGTGMLA 503
            |||||:    |...:..||     |:.:.|.....|..||..|...|..: :|:|:|..|.....
plant   523 LWRMPMEESYWEMMKSGVA-----DMVNFGGRAGGSITAALFLKRFVSENVEWLHIDMAGRVWNE 582

  Fly   504 KHGVPPYLLKDCMTGRPTRSIIQFL 528
            |        |...||....::::::
plant   583 K--------KKAATGFGVATLVEWV 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap8	NP_611132.1	Peptidase_M17	51..528	CDD:238247	127/536 (24%)
S-Lap8	NP_611132.1	PepB	66..532	CDD:223338	122/521 (23%)
AT4G30910	NP_001328632.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1254
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1544
OMA	1	1.010	-	-		QHG61256
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	1	1.000	-	-		FOG0001058
OrthoInspector	1	1.000	-	-		mtm1057
orthoMCL	1	0.900	-	-		OOG6_100682
Panther	1	1.100	-	-	O	PTHR11963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X713
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840