Protein Alignment S-Lap8 and Npepl1

DIOPT Version :9

• Sequence 1: NP_611132.1
• Gene: S-Lap8 / 36844
• FlyBaseID: FBgn0034132
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001365722.1
• Gene: Npepl1 / 228961
• MGIID: 2448523
• Length: 529
• Species: Mus musculus
• Alignment Length: 446
• Identity: 112/446 - (25%)
• Similarity: 179/446 - (40%)
• Gaps: 65/446 - (14%)

  Fly    98 GRLYQNIDKEYWAVA--------------------VVGLGKEGAGFNAEEVIDEGMENVRVCAAV 142
            |:|...:.:|.|..|                    |..|....:..|:..........||.|...
Mouse    41 GKLQPRVTEELWQAALATLNPNPTDSCPLYLNCATVAALPSRVSRHNSPSAAHFITRLVRTCLPP 105

  Fly   143 GAR--ALQLQGCTTCHVDGMEYPEQAAEGAAMA------VWRYNVNKRKKNRIAIPKLELYGSTD 199
            |..  .|...|...|     |..|..|...|:|      ..|...::|.:.|..:.:..|.|..:
Mouse   106 GTHRCILVSAGPMVC-----EQTEVFASACALARAFPLFTHRSGASRRAEKRTVMVEFFLVGQDN 165

  Fly   200 ---QDAWTRGLFKA-ESQNLARRLSDTPANQMTPSIFAQATVDALCPCGVSVEVRSMDWIETQNL 260
               :.:..:.|..| |...||.|:.|||.|:|...||.:..:......|::..:...:.::|:..
Mouse   166 GPVEVSTLQCLTNATEGVRLAARIVDTPCNEMNTDIFLEEIIQVGKELGITPTIIRDEQLKTKGF 230

  Fly   261 NSFLMVAKGSCEPPIILEVSYCGTSPE--ERPILMLGKGLTFNSGGLCLHPKRGMDEYRGAVSGA 323
            .....|.|.:..||.:..:|:   :|:  .:.|..:|||:.:::|||.:..|..|...:....||
Mouse   231 GGIYGVGKAALHPPALAILSH---TPDGATQTIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGA 292

  Fly   324 AVCVAAIRAAAALSLPINVSAVLPLCENMPSGMATKPGDVVTLLNGKTMRIKDISLAGTVLLADP 388
            |..:.|.|||.......|:.||..|.||.....||:|.|:..|.:|||:.|.:....|.::|||.
Mouse   293 AAVLGAFRAAIKQGFKDNLHAVFCLAENAVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADG 357

  Fly   389 LLYAQSTFKPKLVVEVGSM--ASGIRKGLGASATGLWTNNSFLWK-NFQKAGALTGDRLWRMPL- 449
            :.||.......::|::.::  |.||..|...:|.   ..||..|: ...|||...||.:  .||
Mouse   358 VSYACKDLGADIIVDMATLTGAQGIATGKYHAAV---LTNSAEWEAACVKAGRKCGDLV--HPLV 417

  Fly   450 ------WRYFRKLVAPRASYDICSTGEGHASSC----LAAAILYELVPCSDWVHLD 495
                  :..|...||...  :..:..:...|||    :|:.|.::..  ..|||||
Mouse   418 YCPELHFSEFTSAVADMK--NSVADRDNSPSSCAGLFIASHIGFDWP--GVWVHLD 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap8	NP_611132.1	Peptidase_M17	51..528	CDD:238247	112/446 (25%)
		PepB	66..532	CDD:223338	112/446 (25%)
Npepl1	NP_001365722.1	Peptidase_M17	35..492	CDD:238247	112/446 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1683
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840