Protein Alignment Parp16 and PARP16

DIOPT Version :10

• Sequence 1: NP_725583.1
• Gene: Parp16 / 36841
• FlyBaseID: FBgn0034129
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: NP_060321.3
• Gene: PARP16 / 54956
• HGNCID: 26040
• Length: 323
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 87/336 - (25%)
• Similarity: 133/336 - (39%)
• Gaps: 89/336 - (26%)

  Fly    58 DFLGCEALWTIFMAAAWSYRYRTRLRPFPSHWNTIDLV-FNT-LGDAPRLEVLQQQLMHCDYQAC 120
            |.|..:...::|.:|..||:..:.|||||:.:...|.. |.. |.||.:|..|::.|     |:.
Human    16 DMLAADLRCSLFASALQSYKRDSVLRPFPASYARGDCKDFEALLADASKLPNLKELL-----QSS 75

  Fly   121 SPNVVR---LLTDILVDQADRVSLSSLRPCEFQELYAHLGMSP--PKQPPTQIFEVR-----TGK 175
            ..|..|   |::.||..:.  :::.|....||:::....| :|  |...|..:||:.     ..|
Human    76 GDNHKRAWDLVSWILSSKV--LTIHSAGKAEFEKIQKLTG-APHTPVPAPDFLFEIEYFDPANAK 137

  Fly   176 GNE-KGE---AYASLRQENKESVRLGFYGCKLEKVYAL--------LNSQNSLDNGKYLELTCDI 228
            ..| |||   .||             |:|.:||..:::        ||..:....|.|  ||.|:
Human   138 FYETKGERDLIYA-------------FHGSRLENFHSIIHNGLHCHLNKTSLFGEGTY--LTSDL 187

  Fly   229 NEALARSKPQAGVGGSRCGSILRCVAVVEFVFQ---------------DNETSRDK--------- 269
            :.||..|....|...|..|.||.||||.|.:..               |...:|.|
Human   188 SLALIYSPHGHGWQHSLLGPILSCVAVCEVIDHPDVKCQTKKKDSKEIDRRRARIKHSEGGDIPP 252

  Fly   270 KQVIIKDANTMQVSYLLLYGQSCNEYAMERQIKLMAEPARELLNWL-ERYHKKAISLGVGLLIV- 332
            |..::.:...::|.|||:|.|           |.....|...|:|. ..:....|||.:.||::
Human   253 KYFVVTNNQLLRVKYLLVYSQ-----------KPPKSRASSQLSWFSSHWFTVMISLYLLLLLIV 306

  Fly   333 -----SSMAHF 338
                 |:..||
Human   307 SVINSSAFQHF 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Parp16	NP_725583.1	ARTD15_N	53..132	CDD:465641	23/78 (29%)
PARP16	NP_060321.3	ARTD15_N	11..90	CDD:465641	23/78 (29%)
		PARP	102..273	CDD:395519	48/186 (26%)