Protein Alignment Parp16 and PARP16

DIOPT Version :9

• Sequence 1: NP_725583.1
• Gene: Parp16 / 36841
• FlyBaseID: FBgn0034129
• Length: 359
• Species: Drosophila melanogaster
• Sequence 2: NP_060321.3
• Gene: PARP16 / 54956
• HGNCID: 26040
• Length: 323
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 87/336 - (25%)
• Similarity: 133/336 - (39%)
• Gaps: 89/336 - (26%)

  Fly    58 DFLGCEALWTIFMAAAWSYRYRTRLRPFPSHWNTIDLV-FNT-LGDAPRLEVLQQQLMHCDYQAC 120
            |.|..:...::|.:|..||:..:.|||||:.:...|.. |.. |.||.:|..|::.|     |:.
Human    16 DMLAADLRCSLFASALQSYKRDSVLRPFPASYARGDCKDFEALLADASKLPNLKELL-----QSS 75

  Fly   121 SPNVVR---LLTDILVDQADRVSLSSLRPCEFQELYAHLGMSP--PKQPPTQIFEVR-----TGK 175
            ..|..|   |::.||..:.  :::.|....||:::....| :|  |...|..:||:.     ..|
Human    76 GDNHKRAWDLVSWILSSKV--LTIHSAGKAEFEKIQKLTG-APHTPVPAPDFLFEIEYFDPANAK 137

  Fly   176 GNE-KGE---AYASLRQENKESVRLGFYGCKLEKVYAL--------LNSQNSLDNGKYLELTCDI 228
            ..| |||   .||             |:|.:||..:::        ||..:....|.|  ||.|:
Human   138 FYETKGERDLIYA-------------FHGSRLENFHSIIHNGLHCHLNKTSLFGEGTY--LTSDL 187

  Fly   229 NEALARSKPQAGVGGSRCGSILRCVAVVEFVFQ---------------DNETSRDK--------- 269
            :.||..|....|...|..|.||.||||.|.:..               |...:|.|
Human   188 SLALIYSPHGHGWQHSLLGPILSCVAVCEVIDHPDVKCQTKKKDSKEIDRRRARIKHSEGGDIPP 252

  Fly   270 KQVIIKDANTMQVSYLLLYGQSCNEYAMERQIKLMAEPARELLNWL-ERYHKKAISLGVGLLIV- 332
            |..::.:...::|.|||:|.|           |.....|...|:|. ..:....|||.:.||::
Human   253 KYFVVTNNQLLRVKYLLVYSQ-----------KPPKSRASSQLSWFSSHWFTVMISLYLLLLLIV 306

  Fly   333 -----SSMAHF 338
                 |:..||
Human   307 SVINSSAFQHF 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Parp16	NP_725583.1	ARTD15_N	53..132	CDD:375539	23/78 (29%)
PARP16	NP_060321.3	PARP	95..273	CDD:306990	49/193 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CM85
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	45	1.000	Inparanoid score	I5494
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1618442at2759
OrthoFinder	1	1.000	-	-		FOG0008351
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_107575
Panther	1	1.100	-	-	LDO	PTHR21328
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4886
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.900