Protein Alignment CG7848 and ME2

DIOPT Version :10

• Sequence 1: NP_611127.1
• Gene: CG7848 / 36839
• FlyBaseID: FBgn0034127
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_002387.1
• Gene: ME2 / 4200
• HGNCID: 6984
• Length: 584
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 205/545 - (37%)
• Similarity: 302/545 - (55%)
• Gaps: 9/545 - (1%)

  Fly    75 MLNQSNYNKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQQYIYLTYLSRRN 139
            |||... |||:||||.||::|.:.||||..:.|.|.||......|:..|:.:::|||:..:..||
Human    29 MLNPRT-NKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERN 92

  Fly   140 RRLFYYLLLSNPDRFVPM--TDASGSIDLLMVHRMIHSMGQGLYICIKDLGHVSQILSNWPFRCV 202
            .:|||.:|..:.:..:|:  |...|.......|  |....:||:|.|.|.|||..|:.|||...|
Human    93 EKLFYRILQDDIESLMPIVYTPTVGLACSQYGH--IFRRPKGLFISISDRGHVRSIVDNWPENHV 155

  Fly   203 RCLLVSNGASVLSVGDLGVDEMPILFSNLHQNVVYGGIHPAYCLAVMLDVGTNNEELLNDPMYTG 267
            :.::|::|..:|.:|||||..|.|....|.......||.|..||.|.:||||:|..||.||.|.|
Human   156 KAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMG 220

  Fly   268 LRERRCSEKLYDQLFEEFTLSVMQQYGPRALILCKDFEAQKAKKQLELYRERQCIVDVDFQCFAA 332
            |.::|...:.||.|.:||..::..:||...||..:||....|.:.|..|||:.|..:.|.|..||
Human   221 LYQKRDRTQQYDDLIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAA 285

  Fly   333 VALAGVIVCNRLKRVFFSSNVFLFYGAEAINIGMARLCMVLLKREGLIEMKAREKIWFFDANGLV 397
            |||||::...::.....|.:..||.||....:|:|.|.::.:...||.|.:|::|||.||..||:
Human   286 VALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLL 350

  Fly   398 VLGRKDIPEELLEFANQRDP--ILDLVE-AIQELKPNILVGGSSLPNTFTPDVLRAMEKSADQPV 459
            |.|||...:...|......|  |.|..| |:..|||:.::|.:.....|||||:|||....::||
Human   351 VKGRKAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPV 415

  Fly   460 IFALSRPLEQTECSAEDAFSYTKGHCIFISGSKLPPLKYAN-KWYQPGHCTSSYLVAGISCGVML 523
            |||||.|..|.||:||:|::.|:|.|:|.|||...|:|..: :.:.||...:.|:..|::..|:|
Human   416 IFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVIL 480

  Fly   524 AGFTNIPDEAFCVAAERLASLVWPCDLEKRNVYPPMRKIQCISLQIAEAIFSYAFGRGLATLYPQ 588
            ....:|.|..|..||:.|.|.:...:|.:..:|||:..||.:|:.||..:..|.:...:|..||:
Human   481 CNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPE 545

  Fly   589 PENPMEYIKNSMYNPEYRMNIVDVY 613
            ||:..:|:|...:..||...:.|||
Human   546 PEDKAKYVKERTWRSEYDSLLPDVY 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7848	NP_611127.1	PLN03129	81..606	CDD:215594	198/530 (37%)
ME2	NP_002387.1	PLN03129	28..566	CDD:215594	202/539 (37%)