Protein Alignment CG7848 and Menl-1

DIOPT Version :9

• Sequence 1: NP_611127.1
• Gene: CG7848 / 36839
• FlyBaseID: FBgn0034127
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001027428.1
• Gene: Menl-1 / 3772542
• FlyBaseID: FBgn0029154
• Length: 610
• Species: Drosophila melanogaster
• Alignment Length: 535
• Identity: 178/535 - (33%)
• Similarity: 280/535 - (52%)
• Gaps: 5/535 - (0%)

  Fly    82 NKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQQYIYLTYLSRRNRRLFYYL 146
            ||.|||||.||:.|.||||:|..|||.|||.....:...||.:||.:|.||..|.:...||::..
  Fly    56 NKALAFTLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYFQF 120

  Fly   147 LLSNPDRFVPM--TDASGSIDLLMVHRMIHSMGQGLYICIKDLGHVSQILSNWPF-RCVRCLLVS 208
            :..|....:|:  |...|.  ...|:.|::....|::|...|.||:.|||||||. |.|:.:.|:
  Fly   121 VSKNVHAVLPIIYTPTVGL--ACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKAICVT 183

  Fly   209 NGASVLSVGDLGVDEMPILFSNLHQNVVYGGIHPAYCLAVMLDVGTNNEELLNDPMYTGLRERRC 273
            :|..:|.:||||.:.|.|....:.......||.|:..|.:.|||||||:.|..||:|.|||:.|.
  Fly   184 DGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPLYIGLRDERL 248

  Fly   274 SEKLYDQLFEEFTLSVMQQYGPRALILCKDFEAQKAKKQLELYRERQCIVDVDFQCFAAVALAGV 338
            ....|....:||..:|:..:|.:.||..:||....|...|..|:...|..:.|.|..|||.|.|:
  Fly   249 KGDEYVCFVDEFMEAVVSTFGDQTLIHFEDFATPNAFMFLNRYQHCYCHFNDDIQGTAAVGLGGL 313

  Fly   339 IVCNRLKRVFFSSNVFLFYGAEAINIGMARLCMVLLKREGLIEMKAREKIWFFDANGLVVLGRKD 403
            :...|:.:.....:|.:|.||.:..:|:|.|..:.|...||.|..|.:.|:|:|.:|::...||.
  Fly   314 LGIQRITKKPLEEHVIVFAGAGSAAMGIAYLLKMELMSRGLSEADAAKNIYFYDQDGVLTTARKS 378

  Fly   404 IPEELLEFANQRDPILDLVEAIQELKPNILVGGSSLPNTFTPDVLRAMEKSADQPVIFALSRPLE 468
            ||:.|..||........|...::::||:|::|.:|.|..||..::|.|..|.::|.|||.|.|..
  Fly   379 IPDILCVFAKNMKETKSLETLVEQVKPSIIMGATSAPGLFTEKIIRTMAASHERPGIFAFSNPTI 443

  Fly   469 QTECSAEDAFSYTKGHCIFISGSKLPPLKYANKWYQPGHCTSSYLVAGISCGVMLAGFTNIPDEA 533
            ::||:||.|:.::.|..|:.:||..||:::..|...||...:.:....:....|....|.:|||.
  Fly   444 KSECTAEQAYKFSDGKAIYSAGSPFPPVEFNGKRLTPGQANNCFAFPALVLATMTVLATRMPDEI 508

  Fly   534 FCVAAERLASLVWPCDLEKRNVYPPMRKIQCISLQIAEAIFSYAFGRGLATLYPQPENPMEYIKN 598
            |.:||..||......:::...:||.:::...::.:|...:..|....|.|....:||:..|||:.
  Fly   509 FLLAAHELAEFPTNEEMQSGRIYPLVKQANEVAYKIGVKVAKYLIENGYAKRNLEPEDVEEYIEK 573

  Fly   599 SMYNPEYRMNIVDVY 613
            :.|...|..::.:.:
  Fly   574 NSYKLTYGSSLAETW 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7848	NP_611127.1	PLN03129	81..606	CDD:215594	177/526 (34%)
		malic	138..317	CDD:278802	61/181 (34%)
		NAD_bind_1_malic_enz	327..603	CDD:133454	84/275 (31%)
Menl-1	NP_001027428.1	PLN03129	35..582	CDD:215594	178/527 (34%)
		malic	114..292	CDD:278802	61/179 (34%)
		NAD_bind_1_malic_enz	302..576	CDD:133454	83/273 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469226
Domainoid	1	1.000	155	1.000	Domainoid score	I893
eggNOG	1	0.900	-	-		E1_COG0281
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I521
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X340
	8	7.890