Protein Alignment CG7848 and Me2

DIOPT Version :9

• Sequence 1: NP_611127.1
• Gene: CG7848 / 36839
• FlyBaseID: FBgn0034127
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_006525559.1
• Gene: Me2 / 107029
• MGIID: 2147351
• Length: 596
• Species: Mus musculus
• Alignment Length: 545
• Identity: 194/545 - (35%)
• Similarity: 299/545 - (54%)
• Gaps: 9/545 - (1%)

  Fly    75 MLNQSNYNKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQQYIYLTYLSRRN 139
            |||... |||:||||.||::|.:.||||..:.|.|.||......|:..|:.:::|||:..:..||
Mouse    36 MLNPRT-NKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERN 99

  Fly   140 RRLFYYLLLSNPDRFVPM--TDASGSIDLLMVHRMIHSMGQGLYICIKDLGHVSQILSNWPFRCV 202
            .:|||.:|..:.:..:|:  |...|.......|  |....:||:|.|.|.|||..|:.|||...|
Mouse   100 EKLFYRILQDDIESLMPIVYTPTVGLACCQYGH--IFRRPKGLFISISDRGHVRSIVDNWPENHV 162

  Fly   203 RCLLVSNGASVLSVGDLGVDEMPILFSNLHQNVVYGGIHPAYCLAVMLDVGTNNEELLNDPMYTG 267
            :.::|::|..:|.:|||||..|.|....|.......||.|..||.|.:||||:|..||.||.|.|
Mouse   163 KAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMG 227

  Fly   268 LRERRCSEKLYDQLFEEFTLSVMQQYGPRALILCKDFEAQKAKKQLELYRERQCIVDVDFQCFAA 332
            |.::|...:|||.|.:||..::..:||...||..:||....|.:.|..|:::.|..:.|.|..||
Mouse   228 LYQKRDRSQLYDDLMDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYQQKYCTFNDDIQGTAA 292

  Fly   333 VALAGVIVCNRLKRVFFSSNVFLFYGAEAINIGMARLCMVLLKREGLIEMKAREKIWFFDANGLV 397
            |||:|::...|:.....|.:..||.||....:|:|.|.::.:...||.|.:|:.|||.||.:||:
Mouse   293 VALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIVLSMVESGLSEEEAQRKIWMFDKSGLL 357

  Fly   398 VLGRK---DIPEELLEFANQRDPILDLVEAIQELKPNILVGGSSLPNTFTPDVLRAMEKSADQPV 459
            |.||.   |..:|....|..........:|:.:|||::::|.:.....||..|::||....::|:
Mouse   358 VKGRTASIDSNQEPYAHAAPESIPATFEDAVNKLKPSVIIGVAGAGPLFTHGVIKAMASINERPI 422

  Fly   460 IFALSRPLEQTECSAEDAFSYTKGHCIFISGSKLPPLKYAN-KWYQPGHCTSSYLVAGISCGVML 523
            |||||.|..|.||:||||::.|:|.|:|.|||...|:|..: :.:.||...::|:..|::..|:|
Mouse   423 IFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVKLQDGRVFTPGQGNNAYIFPGVALAVIL 487

  Fly   524 AGFTNIPDEAFCVAAERLASLVWPCDLEKRNVYPPMRKIQCISLQIAEAIFSYAFGRGLATLYPQ 588
            ....:|.|..|..||:.|.:.:...:|.:..:||.:..||.:|..||..:..|.:...:|..||:
Mouse   488 CEARHISDTVFLEAAKALTTQLTDAELAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRYPE 552

  Fly   589 PENPMEYIKNSMYNPEYRMNIVDVY 613
            ||:...|::..::...|...:.|||
Mouse   553 PEDKARYVRERIWRSNYVSLLPDVY 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7848	NP_611127.1	PLN03129	81..606	CDD:215594	187/530 (35%)
		malic	138..317	CDD:278802	68/180 (38%)
		NAD_bind_1_malic_enz	327..603	CDD:133454	93/279 (33%)
Me2	XP_006525559.1	PLN03129	35..573	CDD:215594	191/539 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849527
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0281
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D435571at2759
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X340
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.710