Protein Alignment atp11c and CG33298

DIOPT Version :10

• Sequence 1: XP_021328509.1
• Gene: atp11c / 368385
• ZFINID: ZDB-GENE-030616-51
• Length: 1139
• Species: Danio rerio
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1336
• Identity: 388/1336 - (29%)
• Similarity: 610/1336 - (45%)
• Gaps: 325/1336 - (24%)

Zfish     4 RRLNRLCG---GDERRVDS-RTIYVGHRPCPDTEAFIPPK----------FCDNRIVSSKYTVWN 54
            :||. ||.   ||:....| ||:...|.        :|||          |..|:|.::|||:.:
  Fly   209 KRLT-LCNYNTGDKFEERSYRTVVPNHT--------VPPKTPKRDHPNGQFVGNKIRTTKYTLLS 264

Zfish    55 FLPKNLFEQFRRIANFYFLIIFLVQVIVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADN 118
            |:||||.|||.|:||.||:.|.|:..:.: :......:.:|:.||:.|||:|..:||..|..:|.
  Fly   265 FIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDK 329

Zfish   119 EVNKYPVTVL--EDGRSVKKESEKIKVGDVVEVVEDETFPCDLILLQSSREDGTCFVTTASLDGE 181
            .:|.....|.  |..|..|.:.::::|||:|.:..:||.|.|::||::|...|.|::.|..||||
  Fly   330 RINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGE 394

Zfish   182 SNHKTHYTVPDIERDLQVL------TAAIECEQPQPDLYKFVGRMHIYKPEQEEAVRSLGPENLL 240
            :|.|....|...| ::|.:      .:.:|.:.|...||:|.|.  :..|..|..  .:..|.||
  Fly   395 TNLKRREVVRGFE-EMQSIFVPSKFVSRVEADAPTTKLYRFHGA--LIHPTGERV--PISTECLL 454

Zfish   241 LKGATLKNTKEIYGVAVYTGMETKMALNYQGKSQKRSAVEKSIN------AFLLVYLCILISKAV 299
            |:.:.||||..|.|:.||.|.|||..||..|...|||.||:.:|      ..:|:.||::  .|:
  Fly   455 LRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVV--GAI 517

Zfish   300 VCTTLKYVWQSKEGQ-DEPWYNEKTQKEKETNMYLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 363
            .|.    :|.|.... ..|:...........:|::     |.:::|:...:||:|:|||:|:.|.
  Fly   518 GCR----MWLSSFTHFPVPYLPPNKLTANMESMWI-----FWTYIVILQVMIPLSLYVTIELCKI 573

Zfish   364 LGSFFIKWDNDFFDPEIEEGALVNTSDLNEELGQVEYVFTDKTGTLTQNNMEFIECCIDGFQYRH 428
            |..|.|..:.|.||.|..:.......::.|||||::::|||||||||:|.|.|..|.::|..|.|
  Fly   574 LQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNH 638

Zfish   429 RDAHGELDGFTVTDGPLNKLQEKAG----------------------------REKEELFLRALC 465
            ..:.            |.|:..|.|                            .::.:.||..|.
  Fly   639 PPSE------------LEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLA 691

Zfish   466 LCHTVQV---------------------------------------------------------- 472
            :|:||.|
  Fly   692 ICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQ 756

Zfish   473 -------------------------------------------------------------KEET 476
                                                                         |.::
  Fly   757 VVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESESPSPPMKNKS 821

Zfish   477 LSDQI-------------------------DGIDGVLPK---------AEEERGFIASSPDEVAL 507
            ||:.|                         .|....||.         |:....:.|.||||:||
  Fly   822 LSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYEAESPDELAL 886

Zfish   508 VKGAMEYGFTFLGLE-NKNMKIRNRQNDIEEYKLLHVLNFDPVRRRMSVIV-QTKSGDTLLFCKG 570
            |..|..|....|... |:.:..........||::|.||.||..|:.||::| |..|.:.:|:.||
  Fly   887 VNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKG 951

Zfish   571 ADSSIFPRV------RPEEVDRIRLQ--VERNATDGYRTLCVAYKQLSAEEYALADTGLREARLA 627
            |||||.|.:      .||.:.|.:.|  ::|.|.:|.|.|.:|.:.|::.:|.......:|..::
  Fly   952 ADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMS 1016

Zfish   628 LQDREEKLMAMYNQVETGMSLIGATAVEDRLQEEAAETMEALQGAGMKIWVLTGDKMETAKSTCY 692
            |::||.:|...:.::|:.::|:|||.:|||||:...||:.:|..||:.:|||||||.|||.:..|
  Fly  1017 LENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAY 1081

Zfish   693 ACRLFQRGTELLELTVRTLEDGRSKREDRLLELLRDYHRRAVQDAPPVKTGVVTRSWSANQEYG- 756
            :.:||.:..||:.||.|:.:...:.....|.::..|            ||       ::...||
  Fly  1082 SAKLFTQQMELIRLTARSRDAAETAINFYLTDMEND------------KT-------TSTLGYGQ 1127

Zfish   757 --------FIIDGATLSLVMNP------PRDADASLYRGLFLQICQNCTAVLCCRMAPLQKAQIV 807
                    .::||.||:.:::|      |           ||::.:.|.:|||||..|||||.:|
  Fly  1128 SLRKKQRALVVDGKTLTFILDPKSKLILP-----------FLRLSKRCASVLCCRSTPLQKAYLV 1181

Zfish   808 KMVK---NCKGSPITLSIGDGANDVSMILEAHVGIGIKGKEGRQAVRNSDYAIPKLKHLKKLLLA 869
            |:||   |.:    ||:|||||||||||..|.||:||.|:||.|||..:|:.:|:.::|::||||
  Fly  1182 KVVKEELNLR----TLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLA 1242

Zfish   870 HGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGYSQQPLYDAAYLTMYNICFTSMPILAYSLL 934
            ||:..|.|::.::.||||||..|:...|.||.:||:|.|.:.|..||.:||:.|||:|.||..:.
  Fly  1243 HGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVY 1307

Zfish   935 EQHIAIEILLDNATLYREIAKNAML--RWRPFLYWTVL--GIFQGLLFFFGVRFLFSNPALQDNG 995
            ::.:|.::||.|..||    ||..|  .:||..:|.:|  .::|.|:.||.....::...:
  Fly  1308 DKRVAEDLLLKNPYLY----KNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDV---- 1364

Zfish   996 QVFGNWSYGTIVFTVLVFTVTLKLALDTRHWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQR 1060
               |.|.:||.:....:|...:..|::.|.||.::...|..||..:..|:..:..:.......:.
  Fly  1365 ---GIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRS 1426

Zfish  1061 LYFVFANMLSSVSAWLVIIILILLSLLPEILLAVLR 1096
            .|:|.....:|...||||::..::::||.:||..:|
  Fly  1427 SYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVR 1462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atp11c	XP_021328509.1	P-type_ATPase_APLT_Dnf-like	42..982	CDD:319770	349/1168 (30%)
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	349/1168 (30%)