Protein Alignment CG6262 and NTH2

DIOPT Version :10

• Sequence 1: NP_611123.2
• Gene: CG6262 / 36833
• FlyBaseID: FBgn0034121
• Length: 1042
• Species: Drosophila melanogaster
• Sequence 2: NP_009555.1
• Gene: NTH2 / 852286
• SGDID: S000000205
• Length: 780
• Species: Saccharomyces cerevisiae
• Alignment Length: 598
• Identity: 120/598 - (20%)
• Similarity: 221/598 - (36%)
• Gaps: 118/598 - (19%)

  Fly    17 RGVFCEGPLLDAVQRSKMFPDCKHFVDMSCI-FTPAQTLADF---DMFTNCRRNDGSLRFLQMFV 77
            ||.:....||..:..:|.|...:.|:|.:.| ..|...|:..   ..:|:..|........::..
Yeast   176 RGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVDRLSRLITTQFWTSLTRRVDLYNIAEIAR 240

  Fly    78 EKHFNDPGSELEH-WTP-----------------PDWKAQPSFLARISDPEIKQFGSDVNGLWKE 124
            :...:.||::... :.|                 |..|.:..:|.:....|..:..:|..||
Yeast   241 DSKIDTPGAKNPRIYVPYNCPEQYEFYIQASQMNPSLKLEVEYLPKDITAEYVKSLNDTPGL--- 302

  Fly   125 LGRRIKDEVKENPDQYSIIYVPNPFIVPSSNCREYRYWESFWIIRGLLQCGMHQTARGMIDNYLE 189
            |...:::.|..:..:.|:  |..|:.||.....|...|:|:.:..||::......||||:::::.
Yeast   303 LALAMEEHVNPSTGERSL--VGYPYAVPGGRFNELYGWDSYLMALGLIESNKVDVARGMVEHFIF 365

  Fly   190 LVQQYGFVPGCGRIYCSGRSNPPLLIMMVKAYVEVT--KDEQYAIEALPLLETEYDTFISK---- 248
            .:..|..:....|.|...||.||.|..|.....|..  |:...||:   ||:..:...|.:
Yeast   366 EIDHYSKILNANRSYYLCRSQPPFLTDMALLVFEKIGGKNNPNAIQ---LLKRAFRAAIKEYKEV 427

  Fly   249 ----------------HS--VQVKGRTMYQYRDSSAGPRPEAYREDLECV------ASIKSPVVR 289
                            ||  :.:...|...:.|:...|..|.|...||.:      ..||.|.:
Yeast   428 WMSSPRLDSLTGLSCYHSDGIGIPPETEPDHFDTILLPYAEKYNVTLEKLRYLYNEGMIKEPKL- 491

  Fly   290 EVMYTELKSAAESGTNFSSRWYVTVDGSNKGSFRDIKTSAIVPVELNCIVFRSGK----ILAEF- 349
            :..:...::..|||.:.:.|            |..: .:.:..::||.::::..|    ::.|:
Yeast   492 DAFFLHDRAVRESGHDTTYR------------FEGV-CAYLATIDLNSLLYKYEKDIAFVIKEYF 543

  Fly   350 -----NRKAGNTKKADEYQDRACVLVKAIRDNLWNAQAGIWLDYDLVNNKPRNYFCCTNFAPLWA 409
                 :...|....::.:::.|.:....|...:|:..:|.:..|:.......:|...|.|..|||
Yeast   544 GNEYKDENDGTVTDSEHWEELAELRKTRINKYMWDEDSGFFFYYNTKLKCRTSYESATTFWSLWA 608

  Fly   410 RAFPLVDTEKVSKGVMQYIKTNDLDAQYGGVPYTMNKESG--------QNWDHPNVFPPMMFLII 466
            .    :.||:.:|..::  |........||:.....|..|        :.||:|..:.|...|..
Yeast   609 G----LATEEQAKITVE--KALPQLEMLGGLVACTEKSRGPISIDRPIRQWDYPFGWAPHQILAW 667

  Fly   467 EGLENLGTPPAKAMSKRWAHRWVKSNYAAYK----YESFMFEKY----------YCEDFGTSGGS 517
            :||...|   .:.::.|.|:||:   |...|    |...:.|||          ...::|..|..
Yeast   668 KGLSAYG---YQQVATRLAYRWL---YMITKSFVDYNGMVVEKYDVTRGTDPHRVDAEYGNQGAD 726

  Fly   518 SPENTPLGYGWTN 530
            .......|:||.|
Yeast   727 FKGVATEGFGWVN 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6262	NP_611123.2	Trehalase	33..541	CDD:418443	116/582 (20%)
NTH2	NP_009555.1	Trehalase_Ca-bi	135..164	CDD:429490
		Trehalase	192..750	CDD:395961	116/582 (20%)