DRSC/TRiP Functional Genomics Resources

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Protein Alignment wcd and WDSUB1

DIOPT Version :9

Sequence 1:NP_611121.1 Gene:wcd / 36831 FlyBaseID:FBgn0262560 Length:506 Species:Drosophila melanogaster
Sequence 2:NP_001121684.1 Gene:WDSUB1 / 151525 HGNCID:26697 Length:476 Species:Homo sapiens


Alignment Length:302 Identity:60/302 - (19%)
Similarity:93/302 - (30%) Gaps:104/302 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   273 YYSYDLLEAKESKLKLPGAMEFMHRFEV-----SPCGKFIVTAGKFGAIHLLTAKTNELLHSFKQ 332
            |...|..|...|.||       .|.:.|     ||.|..:.:....|...|...:..::|...:|
Human    37 YSLRDFTELPHSPLK-------FHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQ 94

  Fly   333 -------------------EGKVKG--FTWSSDSKRILVCGSTSNVSVLNLRQNLIEHIFMDDGC 376
                               .|...|  ..|::.|.::..|||                  :.||.
Human    95 PSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGS------------------VKDGS 141

  Fly   377 IHGESIQLSPNQRLLATGSQEGVVNIYD--YESIFASKA-----------PQPEK------RFMN 422
            :  .:...|||.....|||..|.:.::|  ...:.:.||           .||..      :|..
Human   142 L--AACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGEQGLQFFR 204

  Fly   423 LRTAITDLQ-------FNH--------SSELLAMCSSEAPNAFKLAH----------FPSATVYS 462
            |.:...|.|       |.|        .|.|...|:.....||  :|          ..|..||.
Human   205 LASCGQDCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLACAF--SHDGQMLVSGSVDKSVIVYD 267

  Fly   463 N-----FPAQNEKVGFVTSMAFSPHSSFLAFATKGKQVPLFR 499
            .     .....:...:||:.||:|::..||..:..|.|.:::
Human   268 TNTENILHTLTQHTRYVTTCAFAPNTLLLATGSMDKTVNIWQ 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wcdNP_611121.1 WD40 <131..444 CDD:225201 45/230 (20%)
WD40 repeat 209..247 CDD:293791
WD40 296..>504 CDD:295369 54/279 (19%)
WD40 repeat 298..332 CDD:293791 7/38 (18%)
WD40 repeat 337..371 CDD:293791 6/35 (17%)
WD40 repeat 376..415 CDD:293791 10/51 (20%)
WD40 repeat 428..465 CDD:293791 13/66 (20%)
WDSUB1NP_001121684.1 WD40 <2..308 CDD:225201 60/299 (20%)
WD40 4..309 CDD:238121 60/300 (20%)
WD 1 10..47 3/9 (33%)
WD40 repeat 16..52 CDD:293791 6/21 (29%)
WD 2 52..91 8/38 (21%)
WD40 repeat 57..93 CDD:293791 7/35 (20%)
WD 3 95..134 4/38 (11%)
WD40 repeat 101..135 CDD:293791 4/33 (12%)
WD 4 137..176 10/40 (25%)
WD40 repeat 142..177 CDD:293791 8/36 (22%)
WD 5 178..228 9/49 (18%)
WD40 repeat 183..236 CDD:293791 9/52 (17%)
WD 6 237..276 7/40 (18%)
WD40 repeat 242..266 CDD:293791 4/25 (16%)
WD 7 279..318 9/31 (29%)
WD40 repeat 284..326 CDD:293791 9/26 (35%)
SAM_WDSUB1 328..399 CDD:188904
SAM 332..395 CDD:197735
U-box 404..476 CDD:252675
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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