Protein Alignment Nup62 and npp-11

DIOPT Version :9

• Sequence 1: NP_001286489.1
• Gene: Nup62 / 36830
• FlyBaseID: FBgn0034118
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_491232.1
• Gene: npp-11 / 171954
• WormBaseID: WBGene00003797
• Length: 805
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 144/545 - (26%)
• Similarity: 206/545 - (37%)
• Gaps: 185/545 - (33%)

  Fly     6 PTTTAAPTGGATSSFSFGLSTGTPAAAPASG---AATTAPATKT--TFSFGTPA---PTAGIGGG 62
            |.||||.| .|||.. ||..|..|::|||:|   .|:||||..|  .||.|..:   |:.|:.|.
 Worm   267 PATTAATT-TATSGL-FGAPTSAPSSAPATGGLFGASTAPAAATGGLFSIGAASASTPSVGLFGN 329

  Fly    63 DADNSKAQAPPAFGFGLGSGTASAPLTLG------TQAAANPASTTSATATGTSAAPPA------ 115
            .:.::.|.|.||        ||.|..:.|      |.|||.|.|:|:....|::||.||
 Worm   330 SSASTTAAAAPA--------TAPAAASTGGLFGATTAAAAAPTSSTTGGLFGSTAAAPAASLPTG 386

  Fly   116 --FGGFT-----AQPAASVV---PTIATSAPNT------------------AATTTGLLGGSGLG 152
              ||..|     |.|.|.:.   .|..||||.|                  ||:|.||.|.|...
 Worm   387 GLFGSSTPAKTPAAPTAGLFGASSTTTTSAPATGSLFGTAPATTTATSAAPAASTGGLFGASSTT 451

  Fly   153 APKTTA-------AASTTLTAAPSAIASTQG-------AAPAPTLSTGGAFANLTTETKTTDSSA 203
            .|.:||       ||:||   ||:|.|.|.|       .|||....|||.|...||.|..|.::.
 Worm   452 TPASTAPTGGLFGAATTT---APAAAAPTGGLFGAATTTAPATVGPTGGLFGAATTTTPATAATL 513

  Fly   204 VSTASQLS--------------------------------------------------------- 211
            ..|.|.:|
 Worm   514 GQTPSTVSATPSLPTTTSTTSTLPKPAEATPTLGLGLGLTSTPLAKGTGWTTSGLKGAATTSAGL 578

  Fly   212 ---------------------------YHQLEEHINKWTLEFEEQEKVFTEQATQINAWDKLLIS 249
                                       :..|:|.:|.:..|..:||:||..:..::||:|:.||:
 Worm   579 KIGASGSDTLSEEEIKAGLGGNDTKAFFTALQEVVNSYHSEIAKQERVFHNKMLELNAYDRELIT 643

  Fly   250 NNGKIV-------ELNDAVKKVKTDQQVLDQELEFIATQQKELEDSLG-----------PLEKEF 296
            ...|::       :|:.:.||:..:...:...|..|.....|||:.|.           ||:..|
 Worm   644 LEPKVLGLYNEMDDLSGSCKKLHFNVASMTSVLNDIEQNVVELENKLSLPEWHTLDYKFPLDSRF 708

  Fly   297 VNLPRVDMERSQTYLMVENLDTQLKQMSEDLKEIIDNLNEANK---GQDTTDPIIQIGKILNAHM 358
            .:  |.|::|.|...|:.|:|:|:|....||.:|..:||....   ...|..|:.:...|:...:
 Worm   709 AS--RHDVQRVQIAQMMLNVDSQMKCADFDLDQITKSLNTMQSTVLKTKTETPLEKTELIMKKQL 771

  Fly   359 NSLQWIESQSTNISKKLEDIGKIQD 383
            ..|..:.:|......||   .|::|
 Worm   772 QKLMDLSTQHDATRDKL---NKLKD 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup62	NP_001286489.1	Nsp1_C	194..300	CDD:309972	32/207 (15%)
		SMC_N	<213..392	CDD:330553	49/192 (26%)
npp-11	NP_491232.1	Nucleoporin_FG	117..218	CDD:290362
		Nucleoporin_FG	220..328	CDD:290362	28/62 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165961
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2196
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002862
OrthoInspector	1	1.000	-	-		oto19198
orthoMCL	1	0.900	-	-		OOG6_102783
Panther	1	1.100	-	-	LDO	PTHR12084
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R852
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.770