Protein Alignment CG7997 and NAGA

DIOPT Version :10

• Sequence 1: NP_611119.1
• Gene: CG7997 / 36829
• FlyBaseID: FBgn0034117
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_000253.1
• Gene: NAGA / 4668
• HGNCID: 7631
• Length: 411
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 191/406 - (47%)
• Similarity: 267/406 - (65%)
• Gaps: 19/406 - (4%)

  Fly    12 ILLLQVLQLSMGLDNGLALKPPMGWMSWERFRCITDCKLYPDECISEKLFQRHADLLVSEGYADA 76
            :||..|.|:.| |||||...|||||::||||||..:|...|..||||:||...||.:..:|:.|.
Human     7 LLLGHVAQVLM-LDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDM 70

  Fly    77 GYEYVIIDDCWLEKNRDNDTQKLVPDRKRFPNGLNALSDHIHNQGLKFGLYQDYGTNTCAGYPG- 140
            ||.|:.|||||: ..|| .:.:|:||.||||:|:..|:|::|:.|||.|:|.|.|..||.||||
Human    71 GYTYLNIDDCWI-GGRD-ASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGT 133

  Fly   141 VIKHMKLDAQTFADWDVDYVKLDGCYANISDMASGYPEFGRLLNETGRPMVYSCSWPAYQEDAGE 205
            .:..:..||||||:|.||.:|||||::...:.|.|||:....||.||||:.:|||||||:   |.
Human   134 TLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYE---GG 195

  Fly   206 MP---DYESLKQHCNLWRNWDDIEDSLESLMQIIDYFAKNQDRIQPHGGPGHWNDPDMLLLGNYG 267
            :|   :|..|...||||||:|||:||..|::.|:::|.::||.:||..||||||||||||:||:|
Human   196 LPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFG 260

  Fly   268 LSYDQSKLQMAIWAIMAAPLIMSNDLAAVRPEIKAILQNRAVIAVDQDELGIQGRRV-LSRNQIE 331
            ||.:||:.|||:|.::||||:||.||..:..:...||||..:|.::||.|||||||: ..::.||
Human   261 LSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKEKSLIE 325

  Fly   332 VWKRPITPVTKSGHHSYAVAFVSRRDDGAPYRIPFTVKELGLTNPKGYNVQDLYDASSKLGVFQS 396
            |:.||::      :.:.|:.|.|.|.| .|||...::.:|..|....|..||:|......|: :.
Human   326 VYMRPLS------NKASALVFFSCRTD-MPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGL-RD 382

  Fly   397 ESQFITRVNPNGVTFY 412
            |:.|...:||:||..:
Human   383 ETNFTVIINPSGVVMW 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7997	NP_611119.1	AmyAc_family	32..315	CDD:476817	146/286 (51%)
		Melibiase_2_C	318..408	CDD:407508	30/90 (33%)
NAGA	NP_000253.1	AmyAc_family	25..308	CDD:476817	146/287 (51%)
		Melibiase_2_C	311..394	CDD:407508	30/90 (33%)