DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7997 and gla

DIOPT Version :9

Sequence 1:	NP_611119.1	Gene:	CG7997 / 36829	FlyBaseID:	FBgn0034117	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001006103.2	Gene:	gla / 450083	ZFINID:	ZDB-GENE-041010-207	Length:	409	Species:	Danio rerio

Alignment Length:	401	Identity:	191/401 - (47%)
Similarity:	264/401 - (65%)	Gaps:	13/401 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLQVLQLSMGLDNGLALKPPMGWMSWERFRCITDCKLYPDECISEKLFQRHADLLVSEGYADAGY 78
            |:.:|..:..|||||||.|.|||:.||||.|.|||...|..||.|:||.:.||::|.||:.||||
Zfish    11 LVCLLVPAAALDNGLALTPTMGWLHWERFMCNTDCDADPQNCIREELFMQMADVMVKEGWKDAGY 75

  Fly    79 EYVIIDDCWLEKNRDNDTQKLVPDRKRFPNGLNALSDHIHNQGLKFGLYQDYGTNTCAGYPGVIK 143
            |:|.|||||..:.||.. .:|..|.||||:|:..|:|::|::|||.|:|.|.||.|||||||.:.
Zfish    76 EFVCIDDCWPSQQRDAQ-GRLQADPKRFPSGIKKLADYVHSKGLKLGIYADVGTKTCAGYPGSLG 139

  Fly   144 HMKLDAQTFADWDVDYVKLDGCY-ANISDMASGYPEFGRLLNETGRPMVYSCSWPAYQEDAGEMP 207
            :..:||:|||||.||.:|.|||: .:...:..||......||:|||.:||||.||.| |...:.|
Zfish   140 YYDIDAKTFADWGVDLLKFDGCFMPDWHQLGEGYINMSSALNQTGRSIVYSCEWPLY-EWQHQQP 203

  Fly   208 DYESLKQHCNLWRNWDDIEDSLESLMQIIDYFAKNQDRIQPHGGPGHWNDPDMLLLGNYGLSYDQ 272
            |||::::.||.|||:.|:.|...|:..|:|:.|:.|..:.|..|||.|||||||::||:|||.||
Zfish   204 DYEAIRKTCNHWRNYGDVYDQWTSVKSILDWTAEKQKIVVPVAGPGGWNDPDMLIIGNFGLSRDQ 268

  Fly   273 SKLQMAIWAIMAAPLIMSNDLAAVRPEIKAILQNRAVIAVDQDELGIQGRRVLSRNQIEVWKRPI 337
            .:.|||:||||||||:|||||..:.|:.|.:|||:.:||::||.||.||.|:|..:..|:|:||:
Zfish   269 QQTQMALWAIMAAPLLMSNDLRDICPKAKELLQNKQIIAINQDPLGKQGYRILKADSFELWERPL 333

  Fly   338 TPVTKSGHHSYAVAFVSRRDDGAPYRIPFTVKEL---GLTNPKGYNVQDLYDASSKLGVFQSESQ 399
                 ||:. .|||.::|::.|.|.|...:|..:   .|.||| .||..:.....::||....|:
Zfish   334 -----SGNR-LAVAVMNRQEIGGPRRFTISVAIMPSWKLCNPK-CNVTQIMPTYKEMGVQNLLSE 391

  Fly   400 FITRVNPNGVT 410
            .:.:|||.|.|
Zfish   392 VVVQVNPTGTT 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7997	NP_611119.1	AmyAc_family	31..408	CDD:298606	180/380 (47%)
gla	NP_001006103.2	Melibiase_2	28..400	CDD:293108	180/380 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596765
Domainoid	1	1.000	358	1.000	Domainoid score	I925
eggNOG	1	0.900	-	-		E1_KOG2366
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H90852
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62673
OrthoDB	1	1.010	-	-		D266390at33208
OrthoFinder	1	1.000	-	-		FOG0001285
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101043
Panther	1	1.100	-	-	O	PTHR11452
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R31
SonicParanoid	1	1.000	-	-		X887
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.750