DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7997 and Gla

DIOPT Version :9

Sequence 1:	NP_611119.1	Gene:	CG7997 / 36829	FlyBaseID:	FBgn0034117	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001102290.2	Gene:	Gla / 363494	RGDID:	1589721	Length:	421	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	180/393 - (45%)
Similarity:	250/393 - (63%)	Gaps:	11/393 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LDNGLALKPPMGWMSWERFRCITDCKLYPDECISEKLFQRHADLLVSEGYADAGYEYVIIDDCWL 88
            ||||||..|.|||:.||||.|..||:..||.||||:||.:.|:|:||:|:.||||||:.|||||:
  Rat    34 LDNGLARTPTMGWLHWERFMCNLDCQEEPDACISEQLFMQMAELMVSDGWRDAGYEYLCIDDCWM 98

  Fly    89 EKNRDNDTQKLVPDRKRFPNGLNALSDHIHNQGLKFGLYQDYGTNTCAGYPGVIKHMKLDAQTFA 153
            ...||: ..:|..|.||||:|:..|::::|::|||.|:|.|.|..||||:||......:||||||
  Rat    99 APERDS-KGRLQADPKRFPSGIKHLANYVHSKGLKLGIYADVGKKTCAGFPGSFGSYDIDAQTFA 162

  Fly   154 DWDVDYVKLDGCYA-NISDMASGYPEFGRLLNETGRPMVYSCSWPAYQEDAGEMPDYESLKQHCN 217
            ||.:|.:|.|||:. ::..:|:||......||.|||.:||||.||.|.... ..|:|..::.:||
  Rat   163 DWGIDLLKFDGCHCDSVVSLANGYKYMSLALNRTGRSIVYSCEWPLYLRPF-HKPNYTDIQYYCN 226

  Fly   218 LWRNWDDIEDSLESLMQIIDYFAKNQDRIQPHGGPGHWNDPDMLLLGNYGLSYDQSKLQMAIWAI 282
            .|||:||:.||.||:..|:.:...:|..|....|||.|||||||::||:|||:||...|||:|||
  Rat   227 HWRNFDDVYDSWESIKSILAWTVTHQKDIVEVAGPGGWNDPDMLVIGNFGLSWDQQVTQMALWAI 291

  Fly   283 MAAPLIMSNDLAAVRPEIKAILQNRAVIAVDQDELGIQGRRVLSRNQIEVWKRPITPVTKSGHHS 347
            |||||:|||||..:..:.||:|||..|||::||.||.||......|:||||:||::.:      :
  Rat   292 MAAPLLMSNDLRQISSQAKALLQNEDVIAINQDPLGKQGYCFRKENEIEVWERPLSNL------A 350

  Fly   348 YAVAFVSRRDDGAP--YRIPFTVKELGLTNPKGYNVQDLYDASSKLGVFQSESQFITRVNPNGVT 410
            :|||..:.::.|.|  |.|..:....||....|..:..:......||.::......||:||:|..
  Rat   351 WAVAVRNLQEIGGPRFYTIQISSLGRGLACNPGCIITQILPEKVHLGFYEWPLTLKTRINPSGTV 415

  Fly   411 FYK 413
            ..:
  Rat   416 LLR 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7997	NP_611119.1	AmyAc_family	31..408	CDD:298606	173/379 (46%)
Gla	NP_001102290.2	Melibiase_2	41..413	CDD:293108	173/379 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354459
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2366
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H90852
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62673
OrthoDB	1	1.010	-	-		D266390at33208
OrthoFinder	1	1.000	-	-		FOG0001285
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101043
Panther	1	1.100	-	-	O	PTHR11452
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X887
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.720