Protein Alignment Vha44 and vma5

DIOPT Version :10

• Sequence 1: NP_725565.3
• Gene: Vha44 / 36826
• FlyBaseID: FBgn0287825
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: NP_593891.1
• Gene: vma5 / 2543469
• PomBaseID: SPAPB2B4.05
• Length: 394
• Species: Schizosaccharomyces pombe
• Alignment Length: 297
• Identity: 92/297 - (30%)
• Similarity: 173/297 - (58%)
• Gaps: 24/297 - (8%)

  Fly   543 SPAELPQYLTRFQWDMAKYPIKQSLRNIADIISKQIGQIDGDLKTKSQAYNNLKGNLQNLEKKKT 607
            ||.|   |::.|.|:.:::.:.:::..|:|.|:.:|...:.|::|:..::.......||::||::
pombe   102 SPLE---YVSSFAWNSSRFHMNKTISEISDRITSEIISFENDIRTRQTSFQQASSAFQNMQKKQS 163

  Fly   608 GSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKVMANDWLTNYEKITDMIVPRSSQLIQEDADYC 672
            |:|..::||::|.:|..:..|:|||.:.:.||..:...:|.:||.:||:::|||::.:.:|:::.
pombe   164 GNLSQKSLANIVHEEDVVHGSDYLTNVFIAVPLNLEKQFLNSYETLTDLVIPRSAKKLDQDSEFV 228

  Fly   673 LFNVTLFKKVAEEFKLHARERKFIVRDFVYNEEELAAGKNEMTKLMTDKKKQFGPLVRWLKVNFS 737
            |:.|.:|||.|:.|...|||.|:.:|:|.:.:......::|.......:|:....|:|:..:.||
pombe   229 LYTVVVFKKTADSFITKAREAKYTIREFTFEQGLRETEQSEFDDAAVKEKRMLSSLLRYASIAFS 293

  Fly   738 EAFCALIHVKALRVFVESVLRYGLPVNFQAILIEPNKKSVKRLRDVLNQLYGHLD---------- 792
            |:|...||:|.|.|:|||:||||||.:|.:::.:|..||..:::::|...|.:|.
pombe   294 ESFQGWIHLKCLCVYVESILRYGLPPDFSSVIFQPMAKSEVKIKNILLSKYAYLAQNPVGNNKVK 358

  Fly   793 --GASAGGAVSSAD-NVDIPGLGFGQSEYFPYVFYKV 826
              .:|||...|.|| |:|        .||.|:|.:.|
pombe   359 NVDSSAGLDESMADLNLD--------EEYLPFVLFTV 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha44	NP_725565.3	V-ATPase_C	5..>98	CDD:472803
		3-helical coiled coil	57..77	CDD:270211
		V-ATPase_C	<547..822	CDD:460851	87/287 (30%)
		3-helical coiled coil	570..596	CDD:270211	6/25 (24%)
		3-helical coiled coil	724..755	CDD:270211	12/30 (40%)
vma5	NP_593891.1	COG5127	1..394	CDD:227456	92/297 (31%)
		3-helical coiled coil	61..81	CDD:270211
		3-helical coiled coil	126..152	CDD:270211	6/25 (24%)
		3-helical coiled coil	280..311	CDD:270211	12/30 (40%)