Protein Alignment Vha44 and Vha44

DIOPT Version :10

• Sequence 1: NP_725565.3
• Gene: Vha44 / 36826
• FlyBaseID: FBgn0287825
• Length: 836
• Species: Drosophila melanogaster
• Sequence 2: XP_315870.4
• Gene: Vha44 / 1276512
• VectorBaseID: AGAMI1_012907
• Length: 385
• Species: Anopheles gambiae
• Alignment Length: 833
• Identity: 323/833 - (38%)
• Similarity: 352/833 - (42%)
• Gaps: 453/833 - (54%)

  Fly     2 MSEYWIISAPGDKTCQQTYDTMNNLTSKQHNLCNNYKFHIPDLKVGTLDQLVGLSDDLGKLDTYV 66
            |:|||:||||||||||||::||||:||||:|||.|:||||||||||||||||||||||||||.||
Mosquito     1 MTEYWLISAPGDKTCQQTWETMNNVTSKQNNLCENFKFHIPDLKVGTLDQLVGLSDDLGKLDGYV 65

  Fly    67 EQITRKVANYLGEVLEDQRDKLHENLMANNSPGPPDDSMPCRHHQRIKHLSLRHQRKHQHTHHQN 131
            ||.|||:|.|||:|||||||||:|||.|||:
Mosquito    66 EQTTRKIAAYLGDVLEDQRDKLYENLQANNN---------------------------------- 96

  Fly   132 KPQHYHHHHHHHQLPQDLKGKSAATCSPATPPAPASAPPHLPPACACDVLAPGSLTGGSLTNLST 196
                                                                             
Mosquito    97 ----------------------------------------------------------------- 96

  Fly   197 SHEPEPEFDVCPCDECFACAPPSTSATASTLLADECYSQTASSMLSATRCALSTVAAIATGSGLG 261
                                                                             
Mosquito    97 ----------------------------------------------------------------- 96

  Fly   262 NGPSTSAAAAAAASNSSGGGGGGGPASCSTLCSSAYFSTSAPTTSSSVHSSMSRSNSKRLNNNTC 326
                                                                             
Mosquito    97 ----------------------------------------------------------------- 96

  Fly   327 SINNNKLSFRSGSHVSQLHLATQQPQHHHSHPHQQPHTNPLQSPVQKSMSEDEGDASNAHEDGET 391
                                                                             
Mosquito    97 ----------------------------------------------------------------- 96

  Fly   392 DEDPKSPHSVQSDLSDAFDWWFNKPKRNSKKSSAQQQHETAQLQHQQTTQQHATPLTPQNHNQYQ 456
                                                                             
Mosquito    97 ----------------------------------------------------------------- 96

  Fly   457 NQHLSKAMTFWHQASTTPRSSYRSFFNSLADQIYSKRSTPSQLNINNGFNLTPTHRSSPVSSCCG 521
                                                                             
Mosquito    97 ----------------------------------------------------------------- 96

  Fly   522 SSSQGRSSPDTDPAEPPEFPLSPAELPQYLTRFQWDMAKYPIKQSLRNIADIISKQIGQIDGDLK 586
                                    :|..|:||||||:||||.||||||||||||||:||||.|||
Mosquito    97 ------------------------DLTSYITRFQWDLAKYPTKQSLRNIADIISKQVGQIDADLK 137

  Fly   587 TKSQAYNNLKGNLQNLEKKKTGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKVMANDWLTNYE 651
            |||.|||||||||||||||::|||||||||||||||||||||||||||||||||....||..:||
Mosquito   138 TKSAAYNNLKGNLQNLEKKQSGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKANMGDWNAHYE 202

  Fly   652 KITDMIVPRSSQLIQEDADYCLFNVTLFKKVAEEFKLHARERKFIVRDFVYNEEELAAGKNEMTK 716
            ||||||||||||.|.:|.||.|..|||||||.:|||||||||||:||:||||||||||||||:||
Mosquito   203 KITDMIVPRSSQTITQDQDYVLCTVTLFKKVVDEFKLHARERKFVVREFVYNEEELAAGKNEITK 267

  Fly   717 LMTDKKKQFGPLVRWLKVNFSEAFCALIHVKALRVFVESVLRYGLPVNFQAILIEPNKKSVKRLR 781
            |:||||||||||||||||||||.|||.:||||||||||||||||||||||||||.|||||.||||
Mosquito   268 LVTDKKKQFGPLVRWLKVNFSECFCAWVHVKALRVFVESVLRYGLPVNFQAILIHPNKKSTKRLR 332

  Fly   782 DVLNQLYGHLDG--ASAGGAVSSADNVDIPGLGFGQSEYFPYVFYKVNIDMVE 832
            |||.||||||||  ||:||   :||||||||||||||||||||:||:||||||
Mosquito   333 DVLQQLYGHLDGSAASSGG---NADNVDIPGLGFGQSEYFPYVYYKLNIDMVE 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha44	NP_725565.3	V-ATPase_C	5..>98	CDD:472803	78/92 (85%)
		3-helical coiled coil	57..77	CDD:270211	15/19 (79%)
		V-ATPase_C	<547..822	CDD:460851	233/276 (84%)
		3-helical coiled coil	570..596	CDD:270211	22/25 (88%)
		3-helical coiled coil	724..755	CDD:270211	27/30 (90%)
Vha44	XP_315870.4	V-ATPase_C	4..372	CDD:460851	78/367 (21%)
		3-helical coiled coil	56..76	CDD:270211	15/19 (79%)
		3-helical coiled coil	121..147	CDD:270211	0/25 (0%)
		3-helical coiled coil	275..306	CDD:270211	0/30 (0%)