DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4282 and ZBTB37

DIOPT Version :9

Sequence 1:NP_611118.3 Gene:CG4282 / 36825 FlyBaseID:FBgn0034114 Length:652 Species:Drosophila melanogaster
Sequence 2:NP_001116242.1 Gene:ZBTB37 / 84614 HGNCID:28365 Length:503 Species:Homo sapiens


Alignment Length:560 Identity:99/560 - (17%)
Similarity:169/560 - (30%) Gaps:212/560 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 QLEVTTIVNQHFPVQISKESDERICGRCWKIVSDFH----TLHEFVSAAQS-------SLQE--- 81
            |||:....|.    .:|..:..|:.||...||.:..    ..|:.|.||.|       ||.|   
Human     8 QLEIPDFSNS----VLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMST 68

  Fly    82 TKVALMEDDPLTQETTSF-------------------------PEIIKLATQEEEGVTEPQELGG 121
            ..::::::..:.::..||                         ..||...||..||:        
Human    69 VSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGI-------- 125

  Fly   122 RNFFYPEIKIEEHELDTLPRIEILERSANTQENQDQLEGAARRLRKRLKAEDGSSVDKDKDE-DG 185
                  ..||...|::.    |:.:.....||...:.......|.:.|.....:.....:.: ..
Human   126 ------HFKINVAEVEA----ELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTPKGNRRGQVSA 180

  Fly   186 VEETAEPAPPKKRRGRPRKSDAAVAPPQ--KPKEDIQ---------------------------- 220
            |.:..|.:||::.           ..||  :|..|::                            
Human   181 VLDIRELSPPEES-----------TSPQIIEPSSDVESREPILRINRAGQWYVETGVADRGGRSD 234

  Fly   221 --------LDLKAEELDEFVDEETDPDFSCLVPSDNSSEDD----------GGSDGFDS------ 261
                    :.:|.|.|:|::..|..|.     ..|.||.::          .||.|.::      
Human   235 DEVRVLGAVHIKTENLEEWLGPENQPS-----GEDGSSAEEVTAMVIDTTGHGSVGQENYTLGSS 294

  Fly   262 ------DSDFELDNGKQEFAVLP--KRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDV 318
                  .:..|:|......:|:|  :|...|.:...:..:|.:|..::....:            
Human   295 GAKVARPTSSEVDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESAM------------ 347

  Fly   319 IIAKFFTSVLPCAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDH 383
                            :.|..:.|..|...::.           |.|            .:|| .
Human   348 ----------------MGVSGYVEYLREQEVSE-----------RWF------------RYNP-R 372

  Fly   384 FKCSVCEKSFQNSRHLESHQQVHMDPAVKLT-FSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFT 447
            ..|..|.|||.....|:.|.::||.    :| |.|.:|.|.:..|..::|| :.||.....|.  
Human   373 LTCIYCAKSFNQKGSLDRHMRLHMG----ITPFVCRMCGKKYTRKDQLEYH-IRKHTGNKPFH-- 430

  Fly   448 CSECNKKFLTERKLKNHMSSMH------------DPESTI 475
            |..|.|.|..:..|..|....|            .||:|:
Human   431 CHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTV 470

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4282NP_611118.3 zf-AD 7..81 CDD:285071 17/60 (28%)
FYDLN_acid <191..268 CDD:302856 20/136 (15%)
C2H2 Zn finger 330..351 CDD:275368 3/20 (15%)
C2H2 Zn finger 360..378 CDD:275368 2/17 (12%)
LIM 361..>400 CDD:295319 9/38 (24%)
C2H2 Zn finger 386..406 CDD:275368 7/19 (37%)
zf-C2H2_8 389..465 CDD:292531 24/76 (32%)
C2H2 Zn finger 417..438 CDD:275368 6/20 (30%)
C2H2 Zn finger 448..465 CDD:275368 5/16 (31%)
C2H2 Zn finger 477..498 CDD:275368
C2H2 Zn finger 511..532 CDD:275368
C2H2 Zn finger 541..562 CDD:275368
C2H2 Zn finger 570..590 CDD:275368
C2H2 Zn finger 598..619 CDD:275368
ZBTB37NP_001116242.1 BTB_POZ_ZBTB37 7..129 CDD:349531 26/138 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 140..206 12/76 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 280..344 11/63 (17%)
C2H2 Zn finger 375..395 CDD:275368 7/19 (37%)
zf-H2C2_2 387..412 CDD:404364 9/28 (32%)
zf-C2H2 401..423 CDD:395048 7/22 (32%)
C2H2 Zn finger 403..423 CDD:275368 6/20 (30%)
zf-H2C2_2 416..438 CDD:404364 8/24 (33%)
C2H2 Zn finger 431..449 CDD:275368 6/17 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 457..503 3/14 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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