Protein Alignment CG4282 and ZFP2

DIOPT Version :9

• Sequence 1: NP_611118.3
• Gene: CG4282 / 36825
• FlyBaseID: FBgn0034114
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_085116.2
• Gene: ZFP2 / 80108
• HGNCID: 26138
• Length: 461
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 88/294 - (29%)
• Similarity: 128/294 - (43%)
• Gaps: 25/294 - (8%)

  Fly   330 CAICNLLVHNFTEMQRHHRLTHQVDPGYMMC--CGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKS 392
            |..|....|..:.:.:|.|: |..:..| .|  ||:.|||...|..|...|.....::|:.|.|:
Human   188 CKECGKAFHKNSSLIQHERI-HTGEKPY-KCNECGKAFTQSMNLTVHQRTHTGEKPYECNECGKA 250

  Fly   393 FQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLT 457
            |..|.||..||:.|..   :..:.|..|.|.|...:.:..|:.| |..:..:|  |::|.|.|..
Human   251 FSQSMHLIVHQRSHTG---EKPYECSQCGKAFSKSSTLTLHQRN-HTGEKPYK--CNKCGKSFSQ 309

  Fly   458 ERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMT 522
            ...|..| ..:|.......|::|||.......|.:|:.:...:||      .:|.:||....|.:
Human   310 STYLIEH-QRLHSGVKPFECNECGKAFSKNSSLTQHRRIHTGEKP------YECMVCGKHFTGRS 367

  Fly   523 GLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKE 585
            .|..| :.||   .||  :.|:.|.|....:..|..| ...|..|:.::|..|.|||.:...|..
Human   368 SLTVH-QVIH---TGEKPYECNECGKAFSQSAYLIEH-QRIHTGEKPYECDQCGKAFIKNSSLTV 427

  Fly   586 HTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLH 619
            |..|||||..|.|..|...|..|.|:.:| ||.|
Human   428 HQRTHTGEKPYQCNECGKAFSRSTNLTRH-QRTH 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	5/20 (25%)
		C2H2 Zn finger	360..378	CDD:275368	8/19 (42%)
		LIM	361..>400	CDD:295319	14/38 (37%)
		C2H2 Zn finger	386..406	CDD:275368	9/19 (47%)
		zf-C2H2_8	389..465	CDD:292531	22/75 (29%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	8/20 (40%)
ZFP2	NP_085116.2	COG5048	99..451	CDD:227381	82/282 (29%)
		C2H2 Zn finger	104..124	CDD:275368
		C2H2 Zn finger	132..152	CDD:275368
		C2H2 Zn finger	160..180	CDD:275368
		C2H2 Zn finger	188..208	CDD:275368	5/20 (25%)
		C2H2 Zn finger	216..236	CDD:275368	8/19 (42%)
		C2H2 Zn finger	244..264	CDD:275368	9/19 (47%)
		C2H2 Zn finger	272..292	CDD:275368	6/20 (30%)
		C2H2 Zn finger	300..320	CDD:275368	6/20 (30%)
		C2H2 Zn finger	328..348	CDD:275368	6/19 (32%)
		C2H2 Zn finger	356..376	CDD:275368	6/20 (30%)
		C2H2 Zn finger	384..404	CDD:275368	5/20 (25%)
		C2H2 Zn finger	412..432	CDD:275368	7/19 (37%)
		C2H2 Zn finger	440..460	CDD:275368	8/20 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910