DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and zgc:153116

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001038888.1	Gene:	zgc:153116 / 751712	ZFINID:	ZDB-GENE-060825-107	Length:	327	Species:	Danio rerio

Alignment Length:	256	Identity:	69/256 - (26%)
Similarity:	111/256 - (43%)	Gaps:	20/256 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 CGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFL 425
            ||:.||.:..|..|...|.......|.:|:|.|.....|.:|.:::.:   :.:|:|:.|.|.|.
Zfish    80 CGKSFTTKDHLKNHTKTHTEKTSLTCKLCKKVFSKYNMLHNHMRIYHE---EKSFTCEHCGKGFT 141

  Fly   426 SKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIIL 490
            .:..:..||......||:   ||..|.:.|..:.|||||:.:..|.:| ::|::||:....|...
Zfish   142 QRGPLKLHKRTHTQDKSK---TCQNCGQFFTQKAKLKNHIKTHLDGKS-LVCEECGRTFYHKEAF 202

  Fly   491 KKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGEHR--CHICAKVSPNARA 553
            .:|.......||      ..|..|...........:| |.||   |||..  |..|.|...:...
Zfish   203 DRHMVAHTGVKP------YHCDQCRRSFAMEAAFDKH-KKIH---AGEKPLVCKQCGKCFYDKLK 257

  Fly   554 LRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKH 614
            |:.|: :.|..|:..||:.|.|:|...::..:|...|.|:..|.|..|..::...|.:..|
Zfish   258 LKGHV-NGHALEKHHKCSKCGKSFLDEEKFNQHMRFHAGKKPYKCVPCKKSYQSKAGLDLH 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368
		C2H2 Zn finger	360..378	CDD:275368	6/16 (38%)
		LIM	361..>400	CDD:295319	11/38 (29%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	22/75 (29%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	7/16 (44%)
		C2H2 Zn finger	477..498	CDD:275368	5/20 (25%)
		C2H2 Zn finger	511..532	CDD:275368	4/20 (20%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	5/19 (26%)
		C2H2 Zn finger	598..619	CDD:275368	4/17 (24%)
zgc:153116	NP_001038888.1	COG5048	<67..226	CDD:227381	42/158 (27%)
		C2H2 Zn finger	77..97	CDD:275368	6/16 (38%)
		C2H2 Zn finger	105..125	CDD:275368	6/19 (32%)
		C2H2 Zn finger	133..153	CDD:275368	6/19 (32%)
		C2H2 Zn finger	161..181	CDD:275368	8/19 (42%)
		C2H2 Zn finger	189..209	CDD:275368	5/19 (26%)
		C2H2 Zn finger	217..237	CDD:275368	4/20 (20%)
		C2H2 Zn finger	245..265	CDD:275368	5/20 (25%)
		C2H2 Zn finger	273..293	CDD:275368	5/19 (26%)
		C2H2 Zn finger	301..319	CDD:275368	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H134721
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000