DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and znf569l

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_017210837.1	Gene:	znf569l / 567317	ZFINID:	ZDB-GENE-110914-7	Length:	444	Species:	Danio rerio

Alignment Length:	432	Identity:	108/432 - (25%)
Similarity:	163/432 - (37%)	Gaps:	88/432 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 QKPKEDIQLD----LKAEELDEFVD-----EETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFELD 268
            ::..||::::    :|.|:|.|..|     ||||.                    .:....||
Zfish     5 KEESEDVKIEDTFTVKQEDLQEQTDLVVLKEETDQ--------------------MEEKQQFE-- 47

  Fly   269 NGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVR--MSRELLEQRKKQQEEYDVIIAKFFTSVLP-- 329
             ..||.....|.|:.   |...|.:|.:||..  :|.:...:|..|:...|:.: :..|...|
Zfish    48 -KPQEIMTNEKPTLT---KKTSRGRPRKPKSECLLSCKQCGKRYSQKSHLDIHM-RVHTKEKPYT 107

  Fly   330 CAICNLLVHNFTEMQ--RHHRLTHQVDPGYMMC--CGRKFTQRKVLAEHVLVHWNPDHFKCSVCE 390
            |..|.   .:|..:|  |.|...|..:..| .|  ||:.|.....|..|:.:|.....|.|:.|.
Zfish   108 CEQCG---KSFGYIQGFRTHMRVHTGERPY-TCQQCGKSFYYAGSLTVHMRIHTGEKPFSCAQCR 168

  Fly   391 KSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKF 455
            |||...::|:.|.:||   .::..::|:.|.|:|   ..|...|.:..|...|..:||..|.:.|
Zfish   169 KSFSQKQNLDIHMKVH---TIEKPYTCEQCGKSF---GYIQGFKTHMRVHTGERPYTCQHCGQTF 227

  Fly   456 LTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKG 520
            ........| ..:|..|....|.:|||..........|..:...:||      ..|..||...|.
Zfish   228 YHAGNFAVH-RRIHTGERPYTCQQCGKTFHHGGNFAAHMRIHTGEKP------YSCPQCGKSFKQ 285

  Fly   521 MTGLKQHMK---------------------SIHVE---SAGE--HRCHICAKVSPNARALRRHIY 559
            ...|:.||:                     |:|:.   ..||  :.|..|.|..|....|..|:
Zfish   286 NGNLEVHMRTHTGERIFTCTQCGKSFTRKQSLHIHMRIHTGEKPYTCTECGKSFPYKNTLNHHM- 349

  Fly   560 HNHECERKFKCTMCEKAFKRPQELKEHTSTHTGEVLYTCPNC 601
            ..|..|:.|.|..|.|:|.....||.|.:.|||.:::||..|
Zfish   350 TTHTEEKPFACAQCGKSFTTKASLKNHMNGHTGTIVFTCDQC 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	13/63 (21%)
		C2H2 Zn finger	330..351	CDD:275368	6/22 (27%)
		C2H2 Zn finger	360..378	CDD:275368	6/19 (32%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		zf-C2H2_8	389..465	CDD:292531	20/75 (27%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	3/16 (19%)
		C2H2 Zn finger	477..498	CDD:275368	5/20 (25%)
		C2H2 Zn finger	511..532	CDD:275368	8/41 (20%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	2/4 (50%)
znf569l	XP_017210837.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910