DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and si:ch73-367f21.4

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_021323881.1	Gene:	si:ch73-367f21.4 / 560465	ZFINID:	ZDB-GENE-120214-27	Length:	1012	Species:	Danio rerio

Alignment Length:	361	Identity:	96/361 - (26%)
Similarity:	146/361 - (40%)	Gaps:	87/361 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   333 CNLLVHN-------------FTEMQ--RHHRLTHQVDPGY------------------------- 357
            |:.::||             ||:|:  ::|...|..|..:
Zfish   545 CHTMIHNGEQTFICSECGKSFTQMRYLKNHMKIHSGDHPFTCPECDKCFTVKQSLETHLKIHTGE 609

  Fly   358 --MMC--CGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCD 418
              .:|  ||:.|..:..|..|:.:|.....:.|.||.|||:..:.||.|..:|..   :..:||.
Zfish   610 KPFICPYCGKNFRIKHSLEGHMRIHTGEKPYPCQVCGKSFREKQSLEKHLTIHTG---EKPYSCP 671

  Fly   419 LCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQ 483
            .|.|:|..|..::.| :..|.  .|..:||.||.|.|..::.||.|| .:|..|....|..|||.
Zfish   672 ECGKSFRVKNCLENH-IKIHT--GEKPYTCQECGKSFTEKQNLKRHM-RIHTGEKPFTCSHCGKS 732

  Fly   484 MRTKIILKKHQELMHSDKPRPEPELQQ-------------------------CQICGAWLKGMTG 523
            .|....||.|..:...:||.   ..||                         |..||...:|...
Zfish   733 FRVSKDLKIHVRIHTGEKPF---SCQQCGKSFSENKKLTSHMRIHTGEKPFVCSHCGKRFRGKQN 794

  Fly   524 LKQHMKSIHVESAGEHR--CHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEH 586
            |:.|:: :|   .||.|  |..|.|.....::|..|| .:|..|:.|.|..|.|:|::.:.||.|
Zfish   795 LESHIR-LH---TGEKRYTCPQCGKSYNEQKSLENHI-RSHTGEKPFACDQCGKSFRQQRILKGH 854

  Fly   587 TSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQ 622
            ...||||..:|||.|..:|.....:.:|: ::|..:
Zfish   855 IRIHTGEKPFTCPQCGKSFIEKTKLERHK-KIHSGE 889

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	7/32 (22%)
		C2H2 Zn finger	360..378	CDD:275368	6/19 (32%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	9/19 (47%)
		zf-C2H2_8	389..465	CDD:292531	25/75 (33%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	7/16 (44%)
		C2H2 Zn finger	477..498	CDD:275368	8/20 (40%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	5/20 (25%)
si:ch73-367f21.4	XP_021323881.1	COG5048	16..447	CDD:227381
		C2H2 Zn finger	39..59	CDD:275368
		C2H2 Zn finger	67..87	CDD:275368
		C2H2 Zn finger	95..115	CDD:275368
		C2H2 Zn finger	123..143	CDD:275368
		C2H2 Zn finger	151..171	CDD:275368
		C2H2 Zn finger	179..199	CDD:275368
		C2H2 Zn finger	207..227	CDD:275368
		C2H2 Zn finger	235..255	CDD:275368
		C2H2 Zn finger	263..283	CDD:275368
		C2H2 Zn finger	291..311	CDD:275368
		COG5048	314..734	CDD:227381	51/195 (26%)
		C2H2 Zn finger	319..339	CDD:275368
		C2H2 Zn finger	347..367	CDD:275368
		C2H2 Zn finger	375..395	CDD:275368
		C2H2 Zn finger	403..423	CDD:275368
		C2H2 Zn finger	431..451	CDD:275368
		C2H2 Zn finger	459..479	CDD:275368
		C2H2 Zn finger	530..550	CDD:275368	1/4 (25%)
		C2H2 Zn finger	558..578	CDD:275368	4/19 (21%)
		COG5048	583..994	CDD:227381	87/323 (27%)
		C2H2 Zn finger	586..606	CDD:275368	0/19 (0%)
		C2H2 Zn finger	614..634	CDD:275368	6/19 (32%)
		C2H2 Zn finger	642..662	CDD:275368	9/19 (47%)
		C2H2 Zn finger	670..690	CDD:275368	6/20 (30%)
		C2H2 Zn finger	698..718	CDD:275368	9/20 (45%)
		C2H2 Zn finger	726..746	CDD:275368	8/19 (42%)
		C2H2 Zn finger	754..774	CDD:275368	2/19 (11%)
		C2H2 Zn finger	782..802	CDD:275368	6/20 (30%)
		C2H2 Zn finger	810..830	CDD:275368	6/20 (30%)
		C2H2 Zn finger	838..858	CDD:275368	7/19 (37%)
		C2H2 Zn finger	866..886	CDD:275368	5/20 (25%)
		C2H2 Zn finger	894..914	CDD:275368
		C2H2 Zn finger	922..942	CDD:275368
		C2H2 Zn finger	950..970	CDD:275368
		C2H2 Zn finger	978..998	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910