DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and ZNF692

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_011542525.1	Gene:	ZNF692 / 55657	HGNCID:	26049	Length:	625	Species:	Homo sapiens

Alignment Length:	194	Identity:	51/194 - (26%)
Similarity:	80/194 - (41%)	Gaps:	44/194 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 CDL--CSKTFLSKTAIDYHKLNKHVPKSEFKFTCSE--CNKKFLTERKLKNHMSSMHDPESTIIC 477
            ||.  |.:.|.::..:::||..:|:.:.  .|:|.|  |.|.|..::.||.|| .:|......||
Human   436 CDFPGCGRIFSNRQYLNHHKKYQHIHQK--SFSCPEPACGKSFNFKKHLKEHM-KLHSDTRDYIC 497

  Fly   478 DKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCH 542
            :.|.:..||...|..|:.:...:||      .||:|||...:....|..|.:. |.|:..
Human   498 EFCARSFRTSSNLVIHRRIHTGEKP------LQCEICGFTCRQKASLNWHQRK-HAETVA----- 550

  Fly   543 ICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTS-THTGEVL--YTCPNCPM 603
                      |||            |.|..|.|.|::|..:..|.| :|...:|  ...|:.|:
Human   551 ----------ALR------------FPCEFCGKRFEKPDSVAAHRSKSHPALLLAPQESPSGPL 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368
		C2H2 Zn finger	360..378	CDD:275368
		LIM	361..>400	CDD:295319
		C2H2 Zn finger	386..406	CDD:275368
		zf-C2H2_8	389..465	CDD:292531	15/51 (29%)
		C2H2 Zn finger	417..438	CDD:275368	6/22 (27%)
		C2H2 Zn finger	448..465	CDD:275368	7/18 (39%)
		C2H2 Zn finger	477..498	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	3/20 (15%)
		C2H2 Zn finger	570..590	CDD:275368	7/20 (35%)
		C2H2 Zn finger	598..619	CDD:275368	2/6 (33%)
ZNF692	XP_011542525.1	zf-C2H2	465..489	CDD:278523	10/24 (42%)
		C2H2 Zn finger	467..489	CDD:275368	9/22 (41%)
		COG5048	490..>591	CDD:227381	32/134 (24%)
		zf-C2H2	495..517	CDD:278523	7/21 (33%)
		C2H2 Zn finger	497..517	CDD:275368	6/19 (32%)
		zf-H2C2_2	509..534	CDD:290200	9/30 (30%)
		C2H2 Zn finger	525..545	CDD:275368	6/20 (30%)
		C2H2 Zn finger	556..577	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910