DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and zgc:171901

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_003200031.1	Gene:	zgc:171901 / 556292	ZFINID:	ZDB-GENE-080220-13	Length:	381	Species:	Danio rerio

Alignment Length:	428	Identity:	107/428 - (25%)
Similarity:	168/428 - (39%)	Gaps:	105/428 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 QKPKEDIQLD----LKAEELDEFV-------DEETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFE 266
            ::..||::::    :|.||.:|..       :|:||   ..|:..:|...           .|.:
Zfish     5 KEESEDVEIEETFTVKHEETEEAFRVKHEDPEEQTD---LMLLKEENQDL-----------KDVQ 55

  Fly   267 LDNGKQEFAVLPKRTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPCA 331
            .::..:|...|..||.  .|.|.:::.|.                             |:...|.
Zfish    56 EEDQPEEQLNLKTRTT--NKSYLQKSVPE-----------------------------TNSSTCQ 89

  Fly   332 IC--------NLLVH-----------------NFTEM--QRHHRLTHQVDPGY-MMCCGRKFTQR 368
            .|        ||.||                 :||:.  .:.|.:.|..:..| ...||:||.|:
Zfish    90 QCGKSFSGKRNLEVHMRIHTGEKPFTCQHCGKSFTQKGNLKSHMIIHSGEKPYACQICGKKFAQK 154

  Fly   369 KVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYH 433
            :..|:|:.:|.....|.|::|.|||....:|:||..:|   :.:..:||..|..||..|..::.|
Zfish   155 RNRADHMRLHTGEKSFTCNLCGKSFTQKGNLKSHLIIH---SGEKPYSCQQCQSTFTQKVHLEQH 216

  Fly   434 KLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMH 498
               ..|...|..|||.:|.|.|..:..|.:||.: |..||..||.:|||....|.....|..:..
Zfish   217 ---MKVHSGEKPFTCDQCGKSFTLKDSLGSHMRA-HTGESQFICHQCGKSFNHKKSFNIHLRVHT 277

  Fly   499 SDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHN 561
            .::|      ..|..||...:....|..|:: :|   .||  |.|.:|.|......:|:.|:. .
Zfish   278 GEEP------YTCCWCGRSFRYKASLDVHIR-VH---TGENPHTCRLCGKSFTQKGSLKAHMI-I 331

  Fly   562 HECERKFKCTMCEKAFKRPQELKEHTSTH-TGEVLYTC 598
            |..|:.|.|..|.|:|:|...|.||...| ..|:|..|
Zfish   332 HTGEKPFTCVQCGKSFRRKLTLNEHVKIHIESELLDQC 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	12/65 (18%)
		C2H2 Zn finger	330..351	CDD:275368	9/47 (19%)
		C2H2 Zn finger	360..378	CDD:275368	7/17 (41%)
		LIM	361..>400	CDD:295319	14/38 (37%)
		C2H2 Zn finger	386..406	CDD:275368	8/19 (42%)
		zf-C2H2_8	389..465	CDD:292531	24/75 (32%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..532	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	8/19 (42%)
		C2H2 Zn finger	598..619	CDD:275368	1/1 (100%)
zgc:171901	XP_003200031.1	COG5048	<38..272	CDD:227381	69/285 (24%)
		C2H2 Zn finger	88..108	CDD:275368	6/19 (32%)
		zf-H2C2_2	100..125	CDD:290200	5/24 (21%)
		C2H2 Zn finger	116..136	CDD:275368	3/19 (16%)
		zf-H2C2_2	128..153	CDD:290200	7/24 (29%)
		C2H2 Zn finger	144..164	CDD:275368	7/19 (37%)
		C2H2 Zn finger	172..192	CDD:275368	8/19 (42%)
		C2H2 Zn finger	200..220	CDD:275368	6/22 (27%)
		zf-H2C2_2	212..236	CDD:290200	8/26 (31%)
		C2H2 Zn finger	228..248	CDD:275368	7/20 (35%)
		C2H2 Zn finger	256..276	CDD:275368	6/19 (32%)
		C2H2 Zn finger	284..304	CDD:275368	5/20 (25%)
		zf-H2C2_2	296..321	CDD:290200	9/28 (32%)
		C2H2 Zn finger	312..332	CDD:275368	5/20 (25%)
		zf-H2C2_2	324..349	CDD:290200	9/25 (36%)
		C2H2 Zn finger	340..360	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910