DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and AgaP_AGAP008232

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_317239.4	Gene:	AgaP_AGAP008232 / 4578130	VectorBaseID:	AGAP008232	Length:	966	Species:	Anopheles gambiae

Alignment Length:	198	Identity:	50/198 - (25%)
Similarity:	75/198 - (37%)	Gaps:	28/198 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 CAICNLLVHNFTEMQRHHRLTHQVDPGYMMC--CGRKFTQRKVLAEH-VLVHWNPDHFKCSVCEK 391
            |.:|:...|:..::..|..::|........|  |.|.::.|..|..| .:||.....|.|..|.|
Mosquito   215 CVVCDRQCHDIDQLDDHLVISHHYPKDAYRCELCPRAYSYRPSLLRHRAIVHGELRRFPCENCPK 279

  Fly   392 SFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFL 456
            .|.:..:|:.|.:.|...|  .:.:|..|.|||.:.:.:..|   .|:..|...|.|..|.|.:.
Mosquito   280 VFTDPSNLQRHIRTHHVGA--RSHACPECGKTFATSSGLKQH---THIHSSVKPFQCEVCFKSYT 339

  Fly   457 TERKLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQ--------------------ELMHSDK 501
            ....|..|.....|.:..|.|:|||....|...|.||:                    :|.|...
Mosquito   340 QFSNLCRHRRMHADCQVQIKCNKCGDSFSTTTSLSKHKRFCDSTAVTRGSLHPGAHPSQLRHPHD 404

  Fly   502 PRP 504
            |.|
Mosquito   405 PYP 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	6/20 (30%)
		LIM	361..>400	CDD:295319	12/39 (31%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	20/75 (27%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	4/16 (25%)
		C2H2 Zn finger	477..498	CDD:275368	9/40 (23%)
		C2H2 Zn finger	511..532	CDD:275368
		C2H2 Zn finger	541..562	CDD:275368
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..619	CDD:275368
AgaP_AGAP008232	XP_317239.4	C2H2 Zn finger	215..237	CDD:275368	4/21 (19%)
		C2H2 Zn finger	245..266	CDD:275368	6/20 (30%)
		zf-C2H2	272..294	CDD:278523	7/21 (33%)
		C2H2 Zn finger	274..294	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..312	CDD:290200	9/27 (33%)
		C2H2 Zn finger	303..323	CDD:275368	7/22 (32%)
		zf-C2H2_8	304..384	CDD:292531	23/82 (28%)
		zf-C2H2	329..351	CDD:278523	6/21 (29%)
		C2H2 Zn finger	331..351	CDD:275368	5/19 (26%)
		C2H2 Zn finger	360..378	CDD:275368	8/17 (47%)
		COG5048	820..>872	CDD:227381
		zf-C2H2	820..842	CDD:278523
		C2H2 Zn finger	822..842	CDD:275368
		zf-H2C2_2	834..858	CDD:290200
		C2H2 Zn finger	850..871	CDD:275368
		zf-C2H2	877..899	CDD:278523
		C2H2 Zn finger	879..899	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910