DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and pzg

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001262143.1	Gene:	pzg / 40351	FlyBaseID:	FBgn0259785	Length:	996	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	55/304 - (18%)
Similarity:	95/304 - (31%)	Gaps:	83/304 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 FKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTC 448
            :||:.|:....:.|...:|.:.    ..:.||.|..|.|.|....|:..|.:..|  .:....||
  Fly   239 YKCTSCDYKTSDMRLFNTHYET----CKQQTFQCKTCRKIFPHFGAMKQHMVRDH--NTAMDNTC 297

  Fly   449 SECNKKFLTERKLKNHMSSMHDPE----------------------------------STIICDK 479
            :.|:..|:.|..|:.||.:.|...                                  |...|:.
  Fly   298 AMCHINFVNENSLRKHMETNHATNVLVTSTTTIPASAAPVAAAAAAAAAAANENLVGTSLYTCNH 362

  Fly   480 CGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHIC 544
            |..:...|::..:|.....:.||:|    .:|::|....:.......|.|.   ......:|..|
  Fly   363 CQFKSTDKVVFDEHMRKHAAGKPKP----FKCRLCSQRFETREAATVHAKQ---HQTNFFKCGTC 420

  Fly   545 AKVSPNARALRRH-----------------IYHNHECERKFKCTMCEKAFKRPQELKEHTSTHTG 592
            :...|....|.:|                 :..|...::..:.|:.|       .|.:.....|.
  Fly   421 SMTFPKREMLVKHFEVHQSPSASTVSPKQSVSQNLNTQKLLQETIDE-------ALSDSLPASTA 478

  Fly   593 EVL-----------YTCPNCPMTFFCSANMYKHRQRLHRAQYEA 625
            .|:           ::|..|.:||. ....|.|....||...:|
  Fly   479 AVVATTESENNIRFFSCSICSLTFI-QETYYNHHMETHRRDKKA 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368
		C2H2 Zn finger	360..378	CDD:275368
		LIM	361..>400	CDD:295319	4/15 (27%)
		C2H2 Zn finger	386..406	CDD:275368	4/19 (21%)
		zf-C2H2_8	389..465	CDD:292531	18/75 (24%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	4/20 (20%)
		C2H2 Zn finger	511..532	CDD:275368	4/20 (20%)
		C2H2 Zn finger	541..562	CDD:275368	5/37 (14%)
		C2H2 Zn finger	570..590	CDD:275368	3/19 (16%)
		C2H2 Zn finger	598..619	CDD:275368	6/20 (30%)
pzg	NP_001262143.1	C2H2 Zn finger	241..263	CDD:275371	4/25 (16%)
		C2H2 Zn finger	268..289	CDD:275371	6/20 (30%)
		C2H2 Zn finger	297..318	CDD:275371	7/20 (35%)
		C2H2 Zn finger	360..380	CDD:275368	4/19 (21%)
		zf-H2C2_2	373..399	CDD:290200	6/29 (21%)
		zf-C2H2_8	375..443	CDD:292531	13/74 (18%)
		C2H2 Zn finger	390..410	CDD:275368	4/22 (18%)
		C2H2 Zn finger	417..437	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100