DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and CkIIalpha-i1

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_524096.2	Gene:	CkIIalpha-i1 / 39721	FlyBaseID:	FBgn0015025	Length:	410	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	72/338 - (21%)
Similarity:	123/338 - (36%)	Gaps:	61/338 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 EPKVRMSRELLEQRKKQQEEYDVIIAKFFTSVLPC-----AICNLLVHNFTEMQRHHRLTHQVDP 355
            :||.:.:.:||::.....:....|:.:.:....||     .|...|....|.....||...::|.
  Fly    22 KPKFKSANKLLQRLFDWYKIDAAILGENYCICEPCFGETLRISESLEKWGTAQDEFHRRPIEIDD 86

  Fly   356 GYMMCCGRKFTQRKVLAEHVLVHWNPDH--FKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCD 418
            ........:.|..|   |.|....|.:.  |...:.|...::......|.::.::.::| |.|.|
  Fly    87 STAFQIKLEVTSNK---EEVETEKNDEENSFDQHIAEPVKEDPLEKNEHMEIVVEESLK-TASVD 147

  Fly   419 LCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTIICDKCGKQ 483
            ..| ..||:..:                    ...||..::.....|          :|..||..
  Fly   148 FFS-VGLSRDGL--------------------AVTKFFKDKTQATRM----------LCTCCGHV 181

  Fly   484 MRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSI-HVES-AG----EHRCH 542
            :.....::     |||.||||.| :..|:.||:....:..|.:|||:: |.:: .|    |..|.
  Fly   182 LEILTHIR-----MHSCKPRPNP-VYYCRDCGSEFHKLHELHEHMKTMKHNKTMCGAKDLEFLCL 240

  Fly   543 ICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTSTH----TGEVLYTCP--NC 601
            .|.::.|....:.||....|... .|.|..|..:|......:.||.:|    |.:..|.||  :|
  Fly   241 RCNQIFPRYFDVIRHENSVHNVS-DFICVECNMSFANQGSYRRHTRSHKVKFTQQRFYECPYKDC 304

  Fly   602 PMTFFCSANMYKH 614
            ..::...|.:..|
  Fly   305 TSSYRVWARLMSH 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	6/25 (24%)
		C2H2 Zn finger	360..378	CDD:275368	4/17 (24%)
		LIM	361..>400	CDD:295319	7/40 (18%)
		C2H2 Zn finger	386..406	CDD:275368	2/19 (11%)
		zf-C2H2_8	389..465	CDD:292531	11/75 (15%)
		C2H2 Zn finger	417..438	CDD:275368	4/20 (20%)
		C2H2 Zn finger	448..465	CDD:275368	2/16 (13%)
		C2H2 Zn finger	477..498	CDD:275368	3/20 (15%)
		C2H2 Zn finger	511..532	CDD:275368	7/21 (33%)
		C2H2 Zn finger	541..562	CDD:275368	5/20 (25%)
		C2H2 Zn finger	570..590	CDD:275368	5/19 (26%)
		C2H2 Zn finger	598..619	CDD:275368	5/19 (26%)
CkIIalpha-i1	NP_524096.2	C2H2 Zn finger	175..191	CDD:275368	3/20 (15%)
		C2H2 Zn finger	203..225	CDD:275368	7/21 (33%)
		C2H2 Zn finger	239..259	CDD:275368	5/19 (26%)
		C2H2 Zn finger	267..287	CDD:275368	5/19 (26%)
		C2H2 Zn finger	299..321	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000909
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.000