DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and CG9932

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_609599.1	Gene:	CG9932 / 34701	FlyBaseID:	FBgn0262160	Length:	2171	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	77/378 - (20%)
Similarity:	128/378 - (33%)	Gaps:	115/378 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   306 LEQRKKQQEEYDVIIAKFFTSVLP-CAI-----CNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRK 364
            ::|:::||.:...:.||  ...|| |.|     ||...: ||:..|:| |||
  Fly    89 VQQQQQQQPQQVGMDAK--EEGLPQCKIKRNYSCNHCAY-FTQNPRYH-LTH------------- 136

  Fly   365 FTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSC---------DLC 420
              .|.|..|.::::      ||.:|   ...|||.:...: ||    |:...|         ...
  Fly   137 --LRDVHGEKIVIN------KCKLC---LYASRHFQKLVR-HM----KMVHGCTDGIPSGHGQAR 185

  Fly   421 SKTFLSKTA-----------IDYHKLNKHVPKSEFKFTCSECNKK-FLTERKLKNHMSSMHDPE- 472
            .|..:|:.|           :....|...||...   |..:..:: .|.|.||:..:.:.:..:
  Fly   186 GKRGMSREARKRRLEESVGVMGGQSLTVTVPDVP---TLEQVKRELLLQEEKLQRDIQAFNQRQR 247

  Fly   473 -----------STIICDKCGKQMRTKIILKKHQELMHSDKPRPEP----------------ELQQ 510
                       ..:......:||:   :|:.::....::.|.|.|                .|.:
  Fly   248 EEQQREQQRELELVATSAYERQMQ---VLRDYERQSPAEPPTPSPTSGSATPPSNGEEPQNRLLK 309

  Fly   511 CQICGAWLKGMTGLKQHMKSIHVESAGEH------RCHICAKVSPNARALRRHI-YHNHECERKF 568
            |..|.......|.|:.|       ...||      ||..|:.|:.......:|: ||:..   ..
  Fly   310 CSACEFTTLYRTQLRAH-------ELAEHGKTKFFRCDKCSYVTHIKARFSKHVKYHSMP---MI 364

  Fly   569 KCTMCEKAFKRPQE--LKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLH 619
            ||..|:  |:.|.:  |..|...|.|...:.|..|..|.....::..|....|
  Fly   365 KCVTCD--FRTPYKWNLDRHMKNHGGAGAFKCAACDFTADIKQSLTVHEMNHH 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	9/25 (36%)
		C2H2 Zn finger	360..378	CDD:275368	3/17 (18%)
		LIM	361..>400	CDD:295319	9/38 (24%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)
		zf-C2H2_8	389..465	CDD:292531	19/96 (20%)
		C2H2 Zn finger	417..438	CDD:275368	5/40 (13%)
		C2H2 Zn finger	448..465	CDD:275368	4/17 (24%)
		C2H2 Zn finger	477..498	CDD:275368	3/20 (15%)
		C2H2 Zn finger	511..532	CDD:275368	5/20 (25%)
		C2H2 Zn finger	541..562	CDD:275368	6/21 (29%)
		C2H2 Zn finger	570..590	CDD:275368	6/21 (29%)
		C2H2 Zn finger	598..619	CDD:275368	4/20 (20%)
CG9932	NP_609599.1	C2H2 Zn finger	339..359	CDD:275368	4/19 (21%)
		C2H2 Zn finger	366..386	CDD:275368	6/21 (29%)
		C2H2 Zn finger	394..414	CDD:275368	4/19 (21%)
		C2H2 Zn finger	816..836	CDD:275370
		C2H2 Zn finger	844..862	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444648
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030