DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and Zfp93

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001100016.1	Gene:	Zfp93 / 296399	RGDID:	1309760	Length:	427	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	75/329 - (22%)
Similarity:	127/329 - (38%)	Gaps:	54/329 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 VHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLES 401
            ||...::.||.|:.....|.....|.:.|:::..|..|:..|.:....||.:|:.:..:|..|:.
  Rat    93 VHGMKDLDRHLRIHTGDKPHKCEFCDKCFSRKDNLTMHMRCHTSVKPHKCHLCDYAAVDSSSLKK 157

  Fly   402 HQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMS 466
            |.::|.|   :..:.|.:|.....:.:.:..| |..|.  .:..|.|..|:.||.....||.||
  Rat   158 HLRIHSD---ERPYKCQMCPYASRNSSQLTVH-LRSHT--GDTPFQCWLCSAKFKISSDLKRHM- 215

  Fly   467 SMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGLKQHMKSI 531
            .:|..|....|:.|..:...|..||.|..:.|:.|         |..|....:....|.:|.: :
  Rat   216 IVHSGEKPFKCEFCDVRCTMKANLKSHIRIKHTFK---------CLHCAFQGRDRADLLEHSR-L 270

  Fly   532 HVESAGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTST------- 589
            | ::....:|..|:....:..|||.| ...|..:|.|||..|....|||..|.:|...
  Rat   271 H-QADHPEKCPECSYSCSSPAALRVH-SRVHCKDRPFKCDFCSFDTKRPSSLAKHIDKVHRERAK 333

  Fly   590 ------------------HTGEVL----YTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKP 632
                              |...::    :.|..|..:|....::     |.|:.|: :|..:.|.
  Rat   334 TENRAPQGKDGPRESGPHHVTNIVTQKAFRCDKCGASFARDDSL-----RCHQKQH-SDWGENKN 392

  Fly   633 PNIL 636
            .|::
  Rat   393 SNLV 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	5/13 (38%)
		C2H2 Zn finger	360..378	CDD:275368	4/17 (24%)
		LIM	361..>400	CDD:295319	9/38 (24%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)
		zf-C2H2_8	389..465	CDD:292531	18/75 (24%)
		C2H2 Zn finger	417..438	CDD:275368	4/20 (20%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	6/20 (30%)
		C2H2 Zn finger	511..532	CDD:275368	4/20 (20%)
		C2H2 Zn finger	541..562	CDD:275368	6/20 (30%)
		C2H2 Zn finger	570..590	CDD:275368	7/44 (16%)
		C2H2 Zn finger	598..619	CDD:275368	4/20 (20%)
Zfp93	NP_001100016.1	COG5048	<96..227	CDD:227381	33/137 (24%)
		zf-H2C2_2	98..123	CDD:290200	6/24 (25%)
		C2H2 Zn finger	114..134	CDD:275368	4/19 (21%)
		C2H2 Zn finger	142..162	CDD:275368	5/19 (26%)
		C2H2 Zn finger	170..190	CDD:275368	4/20 (20%)
		C2H2 Zn finger	198..218	CDD:275368	8/20 (40%)
		zf-H2C2_2	210..234	CDD:290200	8/24 (33%)
		C2H2 Zn finger	226..245	CDD:275368	6/18 (33%)
		C2H2 Zn finger	279..299	CDD:275368	6/20 (30%)
		C2H2 Zn finger	307..328	CDD:275368	7/20 (35%)
		C2H2 Zn finger	364..384	CDD:275368	5/24 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930