Protein Alignment CG4282 and ZNF345

DIOPT Version :9

• Sequence 1: NP_611118.3
• Gene: CG4282 / 36825
• FlyBaseID: FBgn0034114
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001229401.1
• Gene: ZNF345 / 25850
• HGNCID: 16367
• Length: 488
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 86/305 - (28%)
• Similarity: 130/305 - (42%)
• Gaps: 28/305 - (9%)

  Fly   330 CAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQ 394
            |..|.......:.:.||||:.....|...:.||:.|.....|.:|..:|.....::|..|..:|.
Human   176 CKECGKSFSFESALIRHHRIHTGEKPYECIDCGKAFGSGSNLTQHRRIHTGEKPYECKACGMAFS 240

  Fly   395 NSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTER 459
            :...|..||::|..   :..:.|:.|.|.|...:|:..|   :.:...|..:.|.||.|.|.:..
Human   241 SGSALTRHQRIHTG---EKPYICNECGKAFSFGSALTRH---QRIHTGEKPYVCKECGKAFNSGS 299

  Fly   460 KLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGL 524
            .|..| ..:|..|....|.:|.|..|:...|.:||.:...:||      .:|:.||......:.|
Human   300 DLTQH-QRIHTGEKPYECKECEKAFRSGSKLIQHQRMHTGEKP------YECKECGKTFSSGSDL 357

  Fly   525 KQHMKSIHVESAGE--HRCHICAKVSPNARALRRHIYHN--HECERKFKCTMCEKAFKRPQELKE 585
            .||.: ||   .||  :.|..|.|...:...|   |.|.  |..||.::|..|.|:|.....|..
Human   358 TQHHR-IH---TGEKPYECKECGKAFGSGSKL---IQHQLIHTGERPYECKECGKSFSSGSALNR 415

  Fly   586 HTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQ--YEADKN 628
            |...||||..|.|..|...|:..:::.:| ||:|..:  ||. ||
Human   416 HQRIHTGEKPYECKECGKAFYSGSSLTQH-QRIHTGEKLYEC-KN 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	6/20 (30%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	9/38 (24%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	19/75 (25%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	6/22 (27%)
		C2H2 Zn finger	570..590	CDD:275368	6/19 (32%)
		C2H2 Zn finger	598..619	CDD:275368	6/20 (30%)
ZNF345	NP_001229401.1	C2H2 Zn finger	64..84	CDD:275368
		COG5048	88..476	CDD:227381	86/305 (28%)
		C2H2 Zn finger	92..112	CDD:275368
		C2H2 Zn finger	120..140	CDD:275368
		C2H2 Zn finger	148..168	CDD:275368
		C2H2 Zn finger	176..196	CDD:275368	6/19 (32%)
		C2H2 Zn finger	204..224	CDD:275368	5/19 (26%)
		C2H2 Zn finger	232..252	CDD:275368	6/19 (32%)
		C2H2 Zn finger	260..280	CDD:275368	6/22 (27%)
		C2H2 Zn finger	288..308	CDD:275368	7/20 (35%)
		C2H2 Zn finger	316..336	CDD:275368	7/19 (37%)
		C2H2 Zn finger	344..364	CDD:275368	6/20 (30%)
		C2H2 Zn finger	372..392	CDD:275368	6/22 (27%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		C2H2 Zn finger	428..448	CDD:275368	6/20 (30%)
		C2H2 Zn finger	456..476	CDD:275368	2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910