DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4282 and Zfp91

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001162591.1	Gene:	Zfp91 / 246282	RGDID:	628736	Length:	568	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	85/405 - (20%)
Similarity:	159/405 - (39%)	Gaps:	96/405 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 RLKAEDGSSVDKDKDEDGVEETAEP--------APPKKRRGRPRKSDAAVAPPQKPKE------D 218
            ||:..:..:.|||..|:..:::..|        .|.:..|...|.|.:.:...:..:.      .
  Rat   112 RLQCIEKITTDKDPKEEKEDDSVLPQEVSITATRPSRSWRSSSRTSISRLRDSENTRSSRSKTGS 176

  Fly   219 IQLDLKAEELDEFVDEETDPDFSCLVPSDNSSEDDGGSDGFDSDSDFELDNGKQEFAV----LPK 279
            :||..|.|.:.:.:|.:        ||.::.|     ..|..||.:.|    ::|..:    :|.
  Rat   177 LQLVCKTEPITDQLDYD--------VPEEHQS-----PSGISSDEEEE----EEEMLISEEEIPF 224

  Fly   280 RTVVRPKKYKKRTKPAEPKVRMSRELLEQRKKQQE---EYDVIIAKFFTSV-------------- 327
            :...|.:.||...:...||.|.....:::.|:::|   |.:|.:.:....:
  Rat   225 KDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRR 289

  Fly   328 -------LP------------CAI--CNLLVHNFTEMQRHHRLTHQVDPGYMMC----CGRKFTQ 367
                   ||            |.:  |..::.:...:|.|.:..|.:...| :|    |||.|..
  Rat   290 KDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKY-VCPHPSCGRLFRL 353

  Fly   368 RKVLAEHVLVHWNPDHFKCSVCEKSFQNSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDY 432
            :|.|..|...|.:...:.|..|.::|::|.:|..|:.:|..   :....|::|..|...|.::::
  Rat   354 QKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTG---EKPLQCEICGFTCRQKASLNW 415

  Fly   433 HKLNKHVPKSEFKFTCSECNKKFLTERKLKNHMSSMHDPESTI---ICDKCGKQMRTKIILKKHQ 494
            | :.||...|.::|:|:.|.|||..:..:..|.:..| ||..|   :....|..:.:..||..:
  Rat   416 H-MKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSH-PEVLIAEALAANAGALITSTDILGTN- 477

  Fly   495 ELMHSDKPRPEPELQ 509
                     |||..|
  Rat   478 ---------PEPLTQ 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856	17/90 (19%)
		C2H2 Zn finger	330..351	CDD:275368	4/22 (18%)
		C2H2 Zn finger	360..378	CDD:275368	8/21 (38%)
		LIM	361..>400	CDD:295319	12/38 (32%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		zf-C2H2_8	389..465	CDD:292531	20/75 (27%)
		C2H2 Zn finger	417..438	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..465	CDD:275368	5/16 (31%)
		C2H2 Zn finger	477..498	CDD:275368	3/20 (15%)
		C2H2 Zn finger	511..532	CDD:275368
		C2H2 Zn finger	541..562	CDD:275368
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..619	CDD:275368
Zfp91	NP_001162591.1	zf-C2H2_8	311..388	CDD:292531	20/77 (26%)
		C2H2 Zn finger	345..364	CDD:275368	7/18 (39%)
		C2H2 Zn finger	372..392	CDD:275368	6/19 (32%)
		zf-H2C2_2	384..409	CDD:290200	6/27 (22%)
		C2H2 Zn finger	400..420	CDD:275368	5/20 (25%)
		C2H2 Zn finger	430..446	CDD:275368	5/15 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100