DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and Zfp62

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001349654.1	Gene:	Zfp62 / 22720	MGIID:	99662	Length:	914	Species:	Mus musculus

Alignment Length:	290	Identity:	90/290 - (31%)
Similarity:	133/290 - (45%)	Gaps:	17/290 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 CAICNLLVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHVLVHWNPDHFKCSVCEKSFQ 394
            |.:|.....|.:.::.|.||.....|.....||:.:..|..|..|..:|.....:|||.|||||.
Mouse   441 CDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFN 505

  Fly   395 NSRHLESHQQVHMDPAVKLTFSCDLCSKTFLSKTAIDYHKLNKHVPKSEFKFTCSECNKKFLTER 459
            .|..||.|:::|   ..:..|.||.|.|.|.:.:.:   |::|.:...|..:.|.||.|.:::..
Mouse   506 YSSALEQHKRIH---TREKPFGCDECGKAFRNNSGL---KVHKRIHTGERPYKCEECGKAYISLS 564

  Fly   460 KLKNHMSSMHDPESTIICDKCGKQMRTKIILKKHQELMHSDKPRPEPELQQCQICGAWLKGMTGL 524
            .|.|| .|:|..|....||:|.|...|...|..|:::...:||      .:|.:|.......:.|
Mouse   565 SLINH-KSVHPGEKPFKCDECEKAFITYRTLLNHKKIHLGEKP------YKCDVCEKSFNYTSLL 622

  Fly   525 KQHMKSIHVESAGEHRCHICAKVSPNARALRRHIYHNHECERKFKCTMCEKAFKRPQELKEHTST 589
            .|| |.:|.... ...|..|.||..|..:|:.| ...|..|:.::|.:|.||:.....|..|.||
Mouse   623 SQH-KRVHTREK-PFECDRCEKVFRNNSSLKVH-KRIHTGEKPYECDICGKAYISHSSLINHKST 684

  Fly   590 HTGEVLYTCPNCPMTFFCSANMYKHRQRLH 619
            |.|:..|||..|...||.|..:..|: |:|
Mouse   685 HPGKTSYTCDECGKAFFSSRTLISHK-RVH 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	6/20 (30%)
		C2H2 Zn finger	360..378	CDD:275368	5/17 (29%)
		LIM	361..>400	CDD:295319	15/38 (39%)
		C2H2 Zn finger	386..406	CDD:275368	11/19 (58%)
		zf-C2H2_8	389..465	CDD:292531	25/75 (33%)
		C2H2 Zn finger	417..438	CDD:275368	6/20 (30%)
		C2H2 Zn finger	448..465	CDD:275368	6/16 (38%)
		C2H2 Zn finger	477..498	CDD:275368	7/20 (35%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	7/20 (35%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		C2H2 Zn finger	598..619	CDD:275368	7/20 (35%)
Zfp62	NP_001349654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..101
		COG5048	127..542	CDD:227381	33/106 (31%)
		C2H2 Zn finger	133..153	CDD:275368
		C2H2 Zn finger	161..181	CDD:275368
		C2H2 Zn finger	189..209	CDD:275368
		C2H2 Zn finger	217..237	CDD:275368
		C2H2 Zn finger	245..265	CDD:275368
		C2H2 Zn finger	273..293	CDD:275368
		C2H2 Zn finger	301..321	CDD:275368
		C2H2 Zn finger	329..349	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368
		SFP1	<379..458	CDD:227516	3/16 (19%)
		C2H2 Zn finger	385..405	CDD:275368
		C2H2 Zn finger	413..433	CDD:275368
		COG5048	437..850	CDD:227381	90/290 (31%)
		C2H2 Zn finger	441..461	CDD:275368	5/19 (26%)
		C2H2 Zn finger	469..489	CDD:275368	5/19 (26%)
		C2H2 Zn finger	497..517	CDD:275368	11/19 (58%)
		C2H2 Zn finger	525..545	CDD:275368	7/22 (32%)
		C2H2 Zn finger	553..573	CDD:275368	8/20 (40%)
		C2H2 Zn finger	581..601	CDD:275368	7/19 (37%)
		C2H2 Zn finger	609..629	CDD:275368	6/20 (30%)
		C2H2 Zn finger	637..657	CDD:275368	7/20 (35%)
		C2H2 Zn finger	665..685	CDD:275368	7/19 (37%)
		C2H2 Zn finger	693..713	CDD:275368	7/20 (35%)
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
		C2H2 Zn finger	777..797	CDD:275368
		C2H2 Zn finger	805..824	CDD:275368
		C2H2 Zn finger	832..852	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910