DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and T07D10.3

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_493194.2	Gene:	T07D10.3 / 188228	WormBaseID:	WBGene00011583	Length:	377	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	64/298 - (21%)
Similarity:	121/298 - (40%)	Gaps:	70/298 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 VVRPKKYKKRTKPAEPKVRMSREL--LEQRKKQQEEYDVII-AKF------FTSVLPC--AICNL 335
            ||.|.: ::.|.|...:: :|.||  |..:....:.|:..: .||      |..|:||  :.|:|
Worm    35 VVEPLR-QRETCPKCHQI-LSSELSRLWHQFVHMDAYNGFLDGKFQIQLPDFEFVIPCPFSTCSL 97

  Fly   336 LVHNFTEMQRHHRLTHQVDPGYMMCCGRKFTQRKVLAEHV-------LVHWNPD-HFK-----CS 387
            |..:..:.:.|:.|.||  ...:.|||.:|:..|...||:       ...|:.. ||.     |:
Worm    98 LFLDLIDARFHYLLEHQ--SCQLFCCGVRFSDYKTALEHLQGTGSVETEAWDQQKHFLKPVYICN 160

  Fly   388 VCEKSFQNSR----HLESHQQVHMDPAVKLTFSC-DLCSKTFLSK-----------TAIDYHKLN 436
            .|.:::.:..    ||.....:..||..|..|.. :.|.:.|..:           ..::|....
Worm   161 CCNRTWSSRNEYVAHLHGRDHMCPDPVCKYIFETNEKCIRHFFEQHYKHLFLDSRHLLLNYKYFL 225

  Fly   437 KHVPKSEFK----FTCSECNKKFLTERKLKNHMSSMH----DPE---STIICDKCGKQ------- 483
            ::..|.|.:    :.|:.|.::|...:..::|::|.:    |.:   ..|.| |||.|
Worm   226 RYQEKQEERAYGLYVCTTCQRRFRDNKGFQSHVASQNCEFFDRKFFVQVIAC-KCGHQFKYCYYQ 289

  Fly   484 ----MRTKIILKKHQELMHSDKPRPEPELQQCQICGAW 517
                :|...:|::..|  |.::..|...:.: .:|..:
Worm   290 RDVLLRNLPVLREAME--HVEREAPFNNMPE-DVCNIY 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	6/22 (27%)
		C2H2 Zn finger	360..378	CDD:275368	7/24 (29%)
		LIM	361..>400	CDD:295319	12/55 (22%)
		C2H2 Zn finger	386..406	CDD:275368	4/23 (17%)
		zf-C2H2_8	389..465	CDD:292531	15/95 (16%)
		C2H2 Zn finger	417..438	CDD:275368	3/32 (9%)
		C2H2 Zn finger	448..465	CDD:275368	3/16 (19%)
		C2H2 Zn finger	477..498	CDD:275368	8/31 (26%)
		C2H2 Zn finger	511..532	CDD:275368	1/7 (14%)
		C2H2 Zn finger	541..562	CDD:275368
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..619	CDD:275368
T07D10.3	NP_493194.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000