DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4282 and C09F5.3

DIOPT Version :9

Sequence 1:	NP_611118.3	Gene:	CG4282 / 36825	FlyBaseID:	FBgn0034114	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001367485.1	Gene:	C09F5.3 / 182454	WormBaseID:	WBGene00015649	Length:	378	Species:	Caenorhabditis elegans

Alignment Length:	385	Identity:	68/385 - (17%)
Similarity:	124/385 - (32%)	Gaps:	113/385 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 RMSRELLEQRKKQQEEYDVIIAKFFTS--------VLPCAICNLLVHNFTEMQRHHRLTHQVDPG 356
            :|.|.......||:|..|...:....|        :|.|.:|:.:..:.:::|.|
Worm     6 KMKRPHNSSHVKQEERADDSHSNSPASSKSIKQENLLKCELCSTVCSSISQLQSH---------- 60

  Fly   357 YMMCCGRKFTQRKVLAEHVLVHWNPD---------------HFKCSVCEKSFQNSRHLESHQQVH 406
                         .|:|||     |:               ...|..||.:|::......|.:.|
Worm    61 -------------TLSEHV-----PEKKPSISTSNSAPSTKRVACQQCEDTFEDFAQFAIHMKSH 107

  Fly   407 MDPAVKLTFSCDLC--SKTFLSKTAIDYHKLNKHV------------------PKSEF------- 444
            :.......|.|.:|  ...|..|.:...|...:|:                  |:::.
Worm   108 LSSVTSQLFFCPICPVGTPFRDKKSQLEHLTTQHLQIQVTQHICSICDSAFPSPQAQSVHFAEAH 172

  Fly   445 -KFTCSECNKKFLTERKLKNHMSSMHDPESTII-CDKCGKQMRTKIILKKHQELMH--------- 498
             |::|:.|:.:...|:..|.| |..|..:..:. |..|.....:::.|..|.::.|
Worm   173 KKYSCTNCDFETENEKTFKEH-SKQHSRQLIMYGCALCATSYPSQLHLITHVQMSHDQETFYPPS 236

  Fly   499 -------SDKPRPEPELQQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHICAKVSPNARALRR 556
                   |.|..|:..:.||.:|...:.|..||.:|....|.:.....:|..|.:...|..:...
Worm   237 LPIPTPPSPKSTPKQRVLQCSVCDESVLGEDGLDEHRLRKHCKVRFADKCADCQEPLLNETSFVE 301

  Fly   557 HIYHNHECERKFKCTMCEKAFKRPQELKEHTSTH---------------TGEVLYTCPNC 601
            |.. .|..:....|.:|.::.:...::..|.:.|               |....:.||.|
Worm   302 HCL-RHSKDHAHHCPVCRQSLRSDSQIHAHCAYHMSHQDSTSSTSSSPITNGFSFVCPIC 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4282	NP_611118.3	zf-AD	7..81	CDD:285071
		FYDLN_acid	<191..268	CDD:302856
		C2H2 Zn finger	330..351	CDD:275368	4/20 (20%)
		C2H2 Zn finger	360..378	CDD:275368	4/17 (24%)
		LIM	361..>400	CDD:295319	9/53 (17%)
		C2H2 Zn finger	386..406	CDD:275368	5/19 (26%)
		zf-C2H2_8	389..465	CDD:292531	18/103 (17%)
		C2H2 Zn finger	417..438	CDD:275368	5/22 (23%)
		C2H2 Zn finger	448..465	CDD:275368	4/16 (25%)
		C2H2 Zn finger	477..498	CDD:275368	4/20 (20%)
		C2H2 Zn finger	511..532	CDD:275368	6/20 (30%)
		C2H2 Zn finger	541..562	CDD:275368	4/20 (20%)
		C2H2 Zn finger	570..590	CDD:275368	3/19 (16%)
		C2H2 Zn finger	598..619	CDD:275368	3/4 (75%)
C09F5.3	NP_001367485.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910